Alcohol Use in Adolescent Twins and Affiliation with Substance Using Peers

Hill, Jennifer; Emery, Robert E.; Harden, K. Paige; Mendle, Jane; Turkheimer, Eric

doi:10.1007/s10802-007-9161-0

Cited by 41 publications

(42 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similarly, Harden and colleagues (2008) reported support for both rGE and social influence; shared environmental factors were not found to be significant in that sample, which focused on adolescent substance use and peer groups. Finally, Hill and colleagues (2008) found evidence of genetic correlation, but not of social influence. All these reports used different modeling approaches than those employed in the current study.…”

Section: Discussionmentioning

confidence: 93%

“…We are also limited to self-reports, which might be subject to bias. Similarly, some evidence suggests that self-reports of peer behavior overestimate the similarity between one’s own behavior and that of their peers (Hill et al, 2008). Data were only available for men, and there is potential for gender differences in the role of peer influences on drinking (Dick et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Multiple Mechanisms Influencing the Relationship Between Alcohol Consumption and Peer Alcohol Use

Edwards

Maes

Prescott

et al. 2015

Alcoholism Clin & Exp Res

View full text Add to dashboard Cite

Background Alcohol consumption is typically correlated with the alcohol use behaviors of one’s peers. Previous research has suggested that this positive relationship could be due to social selection, social influence, or a combination of both processes. However, few studies have considered the role of shared genetic and environmental influences in conjunction with causal processes. Methods The current study uses data from a sample of male twins (N=1790) who provided retrospective reports of their own alcohol consumption and their peers’ alcohol related behaviors, from adolescence into young adulthood (ages 12–25). Structural equation modeling was employed to compare three plausible models of genetic and environmental influences on the relationship between phenotypes over time. Results Model fitting indicated that one’s own alcohol consumption and the alcohol use of one’s peers are related through both genetic and shared environmental factors and through unique environmental causal influences. The relative magnitude of these factors, and their contribution to covariation, changed over time, with genetic factors becoming more meaningful later in development. Conclusions Peers’ alcohol use behaviors and one’s own alcohol consumption are related through a complex combination of genetic and environmental factors that act via correlated factors and the complementary causal mechanisms of social selection and influence. Understanding these processes can inform risk assessment as well as improve our ability to model the development of alcohol use.

show abstract

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Multiple Mechanisms Influencing the Relationship Between Alcohol Consumption and Peer Alcohol Use

Edwards

Maes

Prescott

et al. 2015

Alcoholism Clin & Exp Res

View full text Add to dashboard Cite

show abstract

“…Similar to the Irons et al (18) study, we found no rGE between ALDH2 *2 status and our measure of the peer environment. Genetic susceptibility for substance use and peer selection are correlated, but likely attributed to other genes than those for alcohol metabolism (40,41). For example, Chassin et al (42) and Mrug and Windle (43), respectively, studied dopamine receptor ( DRD4 ) and μ-opioid receptor M1 ( OPRM1 ) genes in association with alcohol use behaviors and found evidence for both genetically influenced peer selection and gene–environment interaction.…”

Section: Discussionmentioning

confidence: 99%

*ALDH2**2 and peer drinking in East Asian college students

O'Shea

Thomas

Webb

et al. 2017

The American Journal of Drug and Alcohol Abuse

View full text Add to dashboard Cite

Background: The ALDH2*2 allele (A-allele) at rs671 is more commonly carried by Asians and is associated with alcohol-related flushing, a strong adverse reaction to alcohol that is protective against drinking. Social factors, such as having friends who binge drink, also contribute to drinking in Asian youth. Objectives: This study examined the interplay between ALDH2*2, peer drinking, and alcohol consumption in college students. We hypothesized that the relationship between ALDH2*2 and standard grams of ethanol per month would vary based on the level of peer drinking. Methods: Subjects (N = 318, 63.25% female) were East Asian college students in the United States who reported drinking alcohol. Data were from the freshman year of a university survey that included a saliva DNA sample. ALDH2*2 status was coded ALDH2*2(+) (A/G and A/A genotypes) and ALDH2*2(−) (G/G genotype). Peer drinking was students’ perception of how many of their friends “got drunk”. Results: Main effects of ALDH2*2(−) and having more friends who got drunk were associated with greater alcohol consumption. The ALDH2*2 × peer drunkenness interaction showed a stronger positive association with alcohol consumption for ALDH2*2(−) versus ALDH2*2(+) at increasing levels of peer drunkenness. Follow-up comparisons within each peer drunkenness level identified significantly higher alcohol consumption for ALDH2*2(−) compared to ALDH2*2(+) at the all friends got drunk level.Conclusion: There was evidence of a stronger effect for ALDH2*2(−) compared to ALDH2*2(+) with greater alcohol use when students were more exposed to peer drinking. Findings contribute to a growing literature on the interrelationships between genetic influences and more permissive environments for alcohol consumption.

show abstract

“…Jugendliche mit ähnli-chen genetisch angelegten Temperamentsmerkmalen etwa hinsichtlich des Risikoverhaltens könnten sich sowohl zueinander als auch zu Alkohol oder Drogen hingezogen fühlen (Dick et al 2007;Hill et al 2008). So können der Alkohol-und Drogenmissbrauch von Freunden ebenso aufgrund ihrer genetischen Ähnlichkeiten korreliert sein wie aufgrund ihrer Sozialisationserfahrungen, auch wenn der Gruppendruck der Freunde beim jugendlichen Trinken nicht ausschließlich genetisch bedingt ist (Cruz et al 2012).…”

Section: Alkohol Und Drogenmissbrauchunclassified