Alcoholism and schizophrenia: the search for perspectives. A review.

Freed, Earl X.

doi:10.15288/jsa.1975.36.853

Cited by 82 publications

(23 citation statements)

References 88 publications

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“…Several studies have found cannabis among the preferred drugs in 'dually diagnosed' schizophrenics [42]; this may be due to the neurobiological effects of ¢ 9 -THC (e.g., dopamine reuptake, glutamatergic dysfunction). With regard to alcohol, Freed [43] assumed that alcoholism tends to mask psychotic symptoms. Another hypothesis is that schizophrenics use drugs as a self-administered medication, for decrease of depression [44] or negative symptoms [45].…”

Section: Discussionmentioning

confidence: 99%

Relationship between Cannabis Use, Schizotypal Traits, and Cognitive Function in Healthy Subjects

Maß

Bardong²,

Kindl³

et al. 2001

Psychopathology

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This research examined the relationship between cannabis use and schizotypal features. A sample of cannabis users (n = 20) was compared with a matched control group (n = 20). All participants were male students of the University of Hamburg. Subjects completed the Perceptual Aberration Scale and the Schizotypal Personality Questionnaire. A Negative Priming procedure and the Trail Making Test were carried out. A urine sample was obtained from each subject. Cannabis users exceeded controls in schizotypy scores and showed impaired neuropsychological parameters. Only within the cannabis group schizotypy scores correlated with neuropsychological parameters. Furthermore, cannabis users reported more often high-risk factors than controls. These findings indicate that among cannabis users there is an increased number of subjects with schizotypal features; schizotypal subjects seem to be more likely to use cannabis than the general population. Therefore, cannabis use may be a vulnerability indicator for schizophrenia.

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Section: Discussionmentioning

confidence: 99%

Relationship between Cannabis Use, Schizotypal Traits, and Cognitive Function in Healthy Subjects

Maß

Bardong²,

Kindl³

et al. 2001

Psychopathology

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“…Freed (1975) showed the variability of reported incidence of schizophrenia amongst alcoholics to be between 1 and 33%. Likewise, schizophrenics abusing alcohol were reported to be anywhere between 3 and 63%.…”

Section: Alcoholism and Schizophreniamentioning

confidence: 99%

Alcoholic Hallucinosis: a psychiatric enigma–2. Follow‐up Studies

Glass¹

1989

British Journal of Addiction

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“…In fact, all the published studies were carried out on hospitalised patients and hence suffer from the deficiency of being a highly selected population. Freed (1975) reviewed the work published from 1923 to 1970 and found the prevalence of schizophrenia among alcoholics to vary between 1% and 63%. It appeared from his review that the studies with very high rates had highly selected samples.…”

Section: Schizophreniamentioning

confidence: 99%

Alcoholism and Psychiatric Disorder

Peace¹,

G²

1987

Aust N Z J Psychiatry

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Over the past 50 years the relationship between alcoholism and psychiatric disorders, such as depression, anxiety and schizophrenia, has been the subject of a great deal of research. Psychiatric problems have been seen as both a cause and a result of alcoholism. Whatever the relation between alcoholism and psychiatric disorder is, it may have significance for the development of differentially effective treatment strategies. Several authors have argued that the presence and nature of psychiatric symptoms should form the basis of a classification system for alcoholics. Given the potential rewards of such a system for both understanding the aetiology of alcoholism and developing effective treatment strategies, it is important to have a clear picture of the nature and extent of this relationship. This paper reviews critically the published studies of the association between alcoholism and psychiatric disorder and outlines directions for future research.

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Alcoholism and schizophrenia: the search for perspectives. A review.

Cited by 82 publications

References 88 publications

Relationship between Cannabis Use, Schizotypal Traits, and Cognitive Function in Healthy Subjects

Relationship between Cannabis Use, Schizotypal Traits, and Cognitive Function in Healthy Subjects

Alcoholic Hallucinosis: a psychiatric enigma–2. Follow‐up Studies

Alcoholism and Psychiatric Disorder

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