AlGaN/GaN High Electron Mobility Transistors integrated into Wireless Detection System for Glucose and pH in Exhaled Breath Condensate

Abstract

Peltier element cooling is demonstrated to be an effective method for collecting exhaled breath condensate (EBC) on AlGaN/GaN High Electron Mobility Transistors (HEMT). The HEMT sensors have functionalized gate areas for glucose and pH measurement. The current change measured in the HEMTs with EBC shows that the sensitivity of the glucose detection is lower than the glucose concentration in the EBC of healthy person and the pH measurement range includes 7-8, typical of that for human blood. The sensors can be integrated into a wireless data transmission system that allows remote monitoring. Details of the transmitter and receiver design for the transmission system are given. Our work demonstrates the possibility of using AlGaN/GaN HEMTs for extended investigations of airway pathology without the need for clinical visits.

GaN Thin Film Based Light Addressable Potentiometric Sensor for pH Sensing Application

“…Wide band gap GaN-based material systems intensively studied over the last few decades [2][3][4] are alternative options to overcome the above mentioned limitations because of GaN's remarkable properties including excellent chemical stability and biocompatibility. 5) Silicon-based ionsensitive field effect transistors (ISFETs) sensors, electrolyte-insulator-semiconductor (EIS) capacitive sensors [6][7][8][9] and III-V nitride-based ion sensitive sensors [10][11][12] have been widely studied. Among the variants of ISFET sensors, the measured ion concentration is an average over the entire sensing surface in contact with the whole solution.…”