Alginate derived nanoassemblies in drug delivery and tissue engineering

Preman, Namitha K.; Jain, Supriya; Sanjeeva, Sandesh G.; Johnson, Renjith P.

doi:10.1016/b978-0-12-822351-2.00011-5

Cited by 2 publications

(1 citation statement)

References 67 publications

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“…Alginate (ALG) is a natural polymer comprising β-D-mannuronic acid and α-L-guluronic acid extracted from brown seaweed [115]. This biomaterial exhibits several properties, including biocompatibility, gelation capability, low toxicity [196], mild gelation conditions, and simple modifications to prepare alginate derivatives with new properties [197], suggesting its use in biomedical and food industry applications.…”

Section: Alginates-based Compositesmentioning

confidence: 99%

Antimicrobial Activity of Composites-Based on Biopolymers

et al. 2022

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Microorganisms have developed a resistance against some of the most conventional antibiotics. These microorganisms can be self-assembled, forming a microbial biofilm. A microbial biofilm formation is an inherent event on almost any surface, causing countless side effects on human health and the environment. Therefore, multiple scientific proposals have been developed based on renewable sources such as natural polymers. Natural polymers or biopolymers include cellulose, chitosan, starch, collagen, gelatin, hyaluronic acid, alginates, fibrin, and pectin, which are widely found in nature. The biopolymers have displayed many interesting properties, including biocompatibility and biodegradability. Nonetheless, these materials usually have no antimicrobial properties (except for the chitosan) by themselves. Therefore, antimicrobial agents have been incorporated into the natural polymeric matrix, providing an antimicrobial property to the biocomposite. Biocomposites consist of two different materials (one of natural origin) studied as biocompatible and biodegradable drug carriers of antimicrobial agents. In addition, due to the incorporation of antimicrobial agents, biocomposites can inhibit biofilm formation and bacteria proliferation on many surfaces. This review describes this using natural polymers as a platform of antimicrobial agents to form a biocomposite to eliminate or reduce biofilm formation on different surfaces.

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Section: Alginates-based Compositesmentioning

confidence: 99%

Antimicrobial Activity of Composites-Based on Biopolymers

et al. 2022

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Current and Future Perspectives of Bioactive Glasses as Injectable Material

Mîrț,

Ficai,

Oprea

et al. 2024

Nanomaterials

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This review covers recent compositions of bioactive glass, with a specific emphasis on both inorganic and organic materials commonly utilized as matrices for injectable materials. The major objective is to highlight the predominant bioactive glass formulations and their clinical applications in the biomedical field. Previous studies have highlighted the growing interest among researchers in bioactive glasses, acknowledging their potential to yield promising outcomes in this field. As a result of this increased interest, investigations into bioactive glass have prompted the creation of composite materials and, notably, the development of injectable composites as a minimally invasive method for administering the material within the human body. Injectable materials have emerged as a promising avenue to mitigate various challenges. They offer several advantages, including minimizing invasive surgical procedures, reducing patient discomfort, lowering the risk of postoperative infection and decreasing treatment expenses. Additionally, injectable materials facilitate uniform distribution, allowing for the filling of defects of any shape.

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Alginate derived nanoassemblies in drug delivery and tissue engineering

Cited by 2 publications

References 67 publications

Antimicrobial Activity of Composites-Based on Biopolymers

Antimicrobial Activity of Composites-Based on Biopolymers

Current and Future Perspectives of Bioactive Glasses as Injectable Material

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