Alginate Hydrogel Formulation with Ketorolac for the Treatment of Pain Related Sialolithiasis
Cristina Silva,
Gladys Ramos-Yacasi,
Mireia Mallandrich
et al.
Abstract:Sialolithiasis mainly affects the oral salivary glands due to the presence of small stones that obstruct the secretion of saliva. The treatment and control of pain and inflammation during the course of this pathology is essential to guarantee the patient’s comfort. For this reason, a ketorolac calcium cross-linked alginate hydrogel was developed, and it was then applied in the area of the buccal cavity. The formulation was characterized (swelling and degradation profile, extrusion, extensibility, surface morph… Show more
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