Alkaloids from Fumaria judaica

Abstract

The major alkaloids obtained from an Egyptian sample of Fumaria judaica Boiss. were stylopine, protopine and Parfumine (2-hydroxy, 3-methoxy-8-ket~ ochotensane). Coptisine, cheilanthifoline and bicuculline were obtained as minor alkaloids. The alkaloid "fumjudaineu is identical to stylopine.

Alkaloids From Iraqi Species of Papaveraceae

“…From the rhoeadine series, alpinigenine (11), rhoeagenine (12), rhoeadine (13), glaucamine (14), and glaudine (15) were obtained. Three protopine alkaloids, protopine (16), cryptopine (17), and allocryptopine (18), two berberine-tvpes, cheilanthifoline (19) and berberine (20) and the phthalideisoquinoline alkaloid narcotine (21) were also identified.…”

“…acrochaetum, P. bornmuelleri and P. curviscapum are not listed previously in the chemical literature for alkaloidal constituents. The following 21 alkaloids were obtained from small samples which were mainly of herbarium material:-mecambrine (1), roehybrine (2), floripavidine (3), IV-methylasimilobine (4), roemerine (5), corydine (6), isocorydine (7), roemerine Noxide (8), dehydro roemerine (9), liriodenine (10), alpinigenine (11), rhoeagenine (12), rhoeadine (13), glaucamine (14), glaudine (15), protopine (16), cryptopine (17), allocryptopine (18), cheilanthifoline (19), berberine (20), narcotine (21).…”

Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia

“…Other known compounds 2-8 were identified through MS library matching techniques (NIST08s) and subsequent comparison of their melting point, optical rotation, mass spectra and NMR spectra ( 1 H and 13 C) with those reported. Compound 2 was identified as scoulerine (Brochmann-Hanssen, Nielson, 1966;Cheng et al, 2008), compound 3 as cheilanthifoline (Okamoto et al, 1971;Haisova and Slavik, 1973;Yeola and Mali, 1984;Rucker et al, 1994;Cheng et al, 2008), compound 4 as protopine (Abou-Donia et al, 1980;Takahashi et al, 1985;Seger et al, 2004), compound 5 as capnoidine Ribar and Meszaros, 1991;Pilar et al, 2010) whose structure was also confirmed from a X-ray crystal structure (not shown here), compound 6 as bicuculline (Edwards and Handa, 1961;Abou-Donia et al, 1980;Blasko et al, 1982;Elango et al, 1982;Basha et al, 2002), compound 7 as corydecumbine (Basnet et al, 1993) and compound 8 as hydrastine Elango et al, 1982).…”

Alkaloids ofFumaria bracteosa

“…Previous studies of many plants belonging to this genus have shown that these plants are characterized by the presence of benzyltetrahydroisoquinoline-, phthalidisoquinoline-, protopine-, protoberberine-, apoiphine-, cularine-, and benzophenanthridine-al- It is worthy of note that bicuculline, which is major alkaloid in this species, has its importance as a specfic and reversible antagonist of the inhibitory action of gamma-aminobutyric acid (GABA) Protopine: aggregates of needles from methanol (120 mg), m. p. 211-213° C (lit. m. p.209° C (6,13,14).…”