Alkaloids of Croton draconoides

Bettolo, Rinaldo Marini; Scarpati, M.L.

doi:10.1016/s0031-9422(00)81913-5

Cited by 39 publications

(25 citation statements)

References 2 publications

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“…The yellow powder (15.0 mg) obtained after evaporation of the solvent was purified by preparative TLC (Et 2 NH/CH 2 Cl 2 , 1:15 v/ v) and crystallized in acetone/CH 2 Cl 2 to yield pure 9 (7.0 mg). The structure was confirmed by its 1 H NMR spectrum and comparison with literature data (Bettolo and Scarpati, 1979).…”

Section: Isolation Of Catechins and Flavonoids From The Eaementioning

confidence: 52%

“…Important products as anaphylatoxins, opsonins and chemotactic peptides are generated during the process of complement activation aiming at the development of an inflammatory response to the spread of an infection. As it is well known, different higher plants can inhibit the complement activation (Lasure et al, 1994a). Such plants with anti-inflammatory activity are considered good source for down-regulators of the complement system .…”

Section: Introductionmentioning

confidence: 99%

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Complement Inhibiting Properties of Dragon’s Blood from Croton draco

Tsacheva

Rostan²,

Iossifova³

et al. 2004

Zeitschrift Für Naturforschung C

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The latex of Croton draco, its extracts and several latex components have been investigated for their influence on both classical (CP) and alternative (AP) activation pathways of the complement system using a hemolytic assay. The best inhibition was found for the classical pathway. The latex, ethyl acetate and ethyl ether extracts exhibited extremely high inhibition on the CP (94, 90 and 77%, respectively) at a concentration of 1 mg/ml. The flavonoid myricitrin, the alkaloid taspine and the cyclopeptides P1 and P2 showed high inhibition on CP (83, 91, 78 and 63%, respectively) at a concentration of 0.9 mm.

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Section: Isolation Of Catechins and Flavonoids From The Eaementioning

confidence: 52%

Section: Introductionmentioning

confidence: 99%

Complement Inhibiting Properties of Dragon’s Blood from Croton draco

Tsacheva

Rostan²,

Iossifova³

et al. 2004

Zeitschrift Für Naturforschung C

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“…Various therapeutic properties of Dragon's blood (Croton spp.) have been described such as wound and ulcer healing, antidiarrhoeic, anticancer, anti-inflammatory and antirheumatic properties (Bettolo and Scarpati, 1979;Perdue et al, 1979;Chen et al, 1994;Pieters et al, 1995;Phillipson, 1995;Gabriel et al, 1999;Holodniy et al, 1999;Miller et al, 2000).…”

Section: Ethnomedicinal Usesmentioning

confidence: 99%

Dragon's blood: Botany, chemistry and therapeutic uses

Gupta

Bleakley

Gupta

2008

Journal of Ethnopharmacology

308

212

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“…Thus, compounds that show antioxidant activity can be considered as potential anti-neoplastic agents. Since the sap of Croton lechleri has been used in the treatment of several types of tumors (Hartwell, 1969;Bettolo and Scarpati, 1979;Chen et al, 1994), it is important to determine whether this sap has antioxidant activity.…”

Section: Introductionmentioning

confidence: 99%