Alkanes of the essential oil of Cannabis sativa

Hendriks, H.; Malingré, Theo M.; Batterman, S.; Bos, Rein

doi:10.1016/s0031-9422(00)89239-0

Cited by 23 publications

(37 citation statements)

References 8 publications

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“…The terpene compounds, in general, are primarily found in the essential oil of Cannabis rather than in the seed oil (Hendriks et al, 1978) as a result of their production in the glandular structures on the aerial portions of the plant. These compounds are a component of the char-acteristic aroma of Cannabis and may impart some of these properties to the seed oil.…”

Section: Terpenesmentioning

confidence: 99%

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The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition

Leizer

Ribnicky

Poulev

et al. 2000

Journal of Nutraceuticals, Functional & Medical Foods

241

150

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ABSTRACT. The fatty acid and natural product content of hemp seed oil was analyzed by GC-MS and LC-MS. The presence of linoleic acid (LA) and a-linolenic acid (LNA) were confirmed in their previously reported ratio of 3:1 LA:LNA. The presence of b-caryophyllene (740 mg/L), myrcene (160 mg/L), b-sitosterol (100-148 g/L) and trace amounts of methyl salicylate was observed in the oil which had not been previously reported. Trace amounts of cannabidiol (CBD) were also detected. Bioassays were performed with the oil to determine its effectiveness as an antimicrobial agent. Some bioactivity was observed during the primary screening.

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Section: Terpenesmentioning

confidence: 99%

“…Although previously identified only in the essential oils of the Cannabis plant (Hendriks et al, 1978), terpenoid compounds have been identified as being present within the seed oil. Health benefits may be gained from their presence even at concentrations similar to that of CBD.…”

Section: Introductionmentioning

confidence: 99%

The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition

Leizer

Ribnicky

Poulev

et al. 2000

Journal of Nutraceuticals, Functional & Medical Foods

241

150

View full text Add to dashboard Cite

show abstract

“…Hashish looks like a hard yellowish-brownish paste that becomes malleable upon heating and different samples can present a high variety in terms of color, density, content of the active principles and flavor [1]. Besides the biologically active cannabinoids, more than 90 phytocannabinoids have been isolated from Cannabis and its essential oil is a complex mixture containing also monoterpenoids and sesquiterpenoids [5][6][7][8], giving it the typical organoleptic properties. The volatiles constituents of Cannabis have been extensively studied [9] because they represent a potential for chemically fingerprinting different cultivars [10].…”

Section: Introductionmentioning

confidence: 99%

Characterization of the Volatile Components of Cannabis Preparations by Solid-Phase Microextraction Coupled to Headspace-Gas Chromatography with Mass Detector (SPME-HSGC/MS)

Arnoldi¹,

Roda²,

Casagni³

et al. 2017

J Chromatogr Sep Tech

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“…The 'free radical' theory of aging [Barber and Bernheim, 1967] accords well with the fact that lipid peroxidation leads to decreases in CMF [Vladimirov et al, 1980]. HSO contains phytosterols, terpenes and kinds of tocopherol that not only exhibit potent antioxidative properties for scavenging free radicals, but may also act on specific signaling pathways for regulating inflammatory responses [Matthaus and Brühl, 2008;Oomah et al, 2002;Hendriks et al, 1978;Nissen et al, 2009]. CMF is a parameter crucial to the maintenance of cellular function.…”

Section: Edss P For Paired-t Test *mentioning

confidence: 90%

“…HSO contains kinds of antioxidants that not only exhibit potent antioxidative properties for scavenging free radicals, but may also act on specific signaling pathways for regulating inflammatory responses [Matthaus and Brühl, 2008;Oomah et al, 2002;Hendriks et al,1978;Nissen et al, 2009]. EPO is being used in increasing amounts in nutritional and pharmaceutical preparations, and may alleviate various chronic disease states [Horrobin, 1992;Huaug & Mills, 1995;Fan, 1998].…”

Section: Introductionmentioning

confidence: 99%

Erythrocyte membrane fatty acids in multiple sclerosis patients and hot-nature dietary intervention with co-supplemented hemp-seed and evening-primrose oils

Rezapour-Firouzi¹,

Arefhosseini²,

Ebrahimi-Mamaghani³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

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The risk of developing multiple sclerosis (MS) is associated with increased dietary intake of saturated fatty acids. For many years it has been suspected that this disease might be associated with an imbalance between unsaturated and saturated fatty acids. We determined erythrocyte membrane fatty acids levels in Hot nature dietary intervention with co-supplemented hemp seed and evening primrose oils in multiple sclerosis patients. To determine the erythrocyte membrane fatty acids levels and correlate it with expanded disability status scale (EDSS) at baseline after 6 months intervention in MS patients by gas chromatography, in this double blind, randomized trial, 100 RRMS patients with EDSS<6 were allocated into three groups: "Group A" that received co-supplemented hemp seed and evening primrose oils with advised Hot nature diet. "Group B" received olive oil and "Group C" received the co-supplemented oils. The results showed that the mean follow-up was 180±2.9SD days (N=65, 23 M and 42 F aged 34.25±8.07 years with disease duration of 6.80±4.33 years). There was no significant difference in the study parameters at baseline. After 6 months, EDSS, Immunological parameters and the erythrocyte cell membrane with regard to specific fatty acids showed improvement in the group A and C, whereas there was worsening condition for the group B after the intervention. We concluded that Hot-nature dietary intervention with co-supplemented hemp seed and evening primrose oils caused an increase PUFAs in MS patients and improvement in the erythrocyte membrane fatty acids composition. This could be an indication of restored plasma stores, and a reflection of disease severity reduction.

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Alkanes of the essential oil of Cannabis sativa

Cited by 23 publications

References 8 publications

The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition

The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition

Characterization of the Volatile Components of Cannabis Preparations by Solid-Phase Microextraction Coupled to Headspace-Gas Chromatography with Mass Detector (SPME-HSGC/MS)

Erythrocyte membrane fatty acids in multiple sclerosis patients and hot-nature dietary intervention with co-supplemented hemp-seed and evening-primrose oils

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