Alkylsulfonium salts for the photochemical desulphurizative functionalization of heteroarenes

Abstract

The development of new versatile alkylation reagents which can be transformed from diverse available chemical raw materials is highly desirable. Here, an efficient, metal-free organic photoredox catalyzed direct alkylation of...

Progress in the decarboxylative deuteration reaction of alkyl carboxylic acids

“…In recent years, photocatalytic chemical reactions have made significant advancements in synthetic chemistry. [26][27][28][29][30][31][32][33] Photocatalysis is an emerging synthetic method that has advantages such as mild reaction conditions, high efficiency, and low energy consumption. Photocatalytic reactions typically utilize ultraviolet or visible light as the light source and employ photocatalysts as mediators to promote the reactions.…”

Photocatalytic C(sp3) radical generationviaC–H, C–C, and C–X bond cleavage

“…Alkyl sulfonium salt can be easily synthesised from alkyl halides, thiols and alcohols. [164][165][166][167][168] Upon receiving an electron, such a trivalent species undergoes R-S cleavage to release an Rc and a thioether. In 2018, MacMillan et al disclosed a Cu(II)/Ir(III) dual photocatalytic system to couple aryl bromides and tri-uoromethylsulfonium salt in the presence of a supersilanol (Scheme 41A).…”

Visible light-mediated three-component functionalization of olefins with sulfoxyimidoylsulfonium salt for the synthesis of β-amino alcohols and amino ethers

“…[15][16][17][18][19][20][21] It is noteworthy that some studies using sulfonium salts as free radical initiators for visible light catalyzed organic synthesis have been reported. [22][23][24][25][26][27][28] In particular, Ritter's group developed a reaction for the amination of alkyl allylamines from olefins with allyl amines of sulfonium ylide structures, and the work was the first visible light amination reaction using a sulfonium salt. 24 In 2021, Alcarazo's group reported the use of sulfoxyimidoylsulfonium salt as a N-centered radical precursor for C-H bond amination.…”