All formulations of hydroxyethyl starch are not the same

Fibrinogen estimates are influenced by methods of measurement and hemodilution with colloid plasma expanders

“…However, interindividual variability is lost and the results have reduced external validity, why larger studies including blood samples from bleeding patients are desirable. This work only investigated HES 130/0.4; thus it should be mentioned that the C2:C6 hydroxylation ratio of various types of HES express different effects on haemostasis 22 . Dilution levels at 30 and 50% were chosen as they represent high but clinical relevant levels during massive bleeding and fluid resuscitation.…”