Allele frequencies of combined DNA index system (CODIS) and non-CODIS short tandem repeat loci in Goiás, Central Brazil

Abstract

ABSTRACT. In studies of human identification, obtaining a high standard of outcomes and satisfactory conclusions are directly related to the use of highly polymorphic molecular markers. In addition to the combined DNA index system (CODIS) group, it is also important to implement non-CODIS markers into the analysis, as they increase the power of discrimination. During the identification process, it is essential to consider the genetic variation among distinct groups of populations, as the allele frequencies 7311 CODIS and non-CODIS STR allele frequencies in Brazil ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (3): 7310-7314 (2015) are directly associated with the power of discrimination. However, the population of Goiás, a State located in Central Brazil, is characterized by a highly mixed population due to its diverse ethnic origins. In this study, a survey of the allelic frequencies in the Goiás population was carried out using a molecular assembly composed of 21 autosomal loci both from and external to the CODIS group. The new data, for some of the markers used, were statistically similar to those from previous studies. This consistency means that the use of these markers might serve as a parameter for future population comparisons. The results from these analyses further our knowledge of the study of human identification.

RETRACTED: Genetic polymorphism and phylogenetic analyses of 21 non‐CODIS STR loci in a Chinese Han population from Shanghai

“…Population data on CODIS STRs in the Shanghai_Han population have been reported and updated for routine forensic applications, such as personal identification and paternity testing. However, extra STRs are needed, since joint analysis of non-CODIS STRs and CODIS STRs has been reported to be significantly informative in identifying problematic kinship cases when a definite conclusion could not be obtained with only the profile of CODIS STRs (Asamura, Fujimori, Ota, & Fukushima, 2007;Rodovalho et al, 2015). Commercial STR kits enable consistency in marker use and allele nomenclature among laboratories and help improve quality control.…”

Development of a polymorphic short tandem repeat locus multiplex system for efficient human identification

“…In this sense, Poetsch et al (2013) concluded that the number of hypervariable loci available for a genetic linkage analysis is directly associated with the percentage of certainty established during the assessment of the analysis (Børsting et al, 2008;Rodovalho et al, 2015;Zhang et al, 2015). Therefore, it is critical that STR panels provide sufficient security, permitting an accurate and unfailing conclusion regarding the genetic linkage analysis.…”