Allergen immunotherapy for asthma

Abramson, Michael J.; Puy, Robert; Weiner, John M.

doi:10.1002/14651858.cd001186

Cited by 325 publications

(242 citation statements)

References 172 publications

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“…Immunotherapy should not be regarded as an alternative to established forms of preventive therapy. Numerous studies have been conducted to explore the role of immunotherapy in asthma (Abramson et al, 2010). The comparison was difficult because of the inherent problems of trials involving asthma, different allergen extract and dosage regimens.…”

Section: Immunotherapy In Asthmamentioning

confidence: 99%

An Overview and Update on Asthma and its Management

Rajanandh¹

2015

J. of Medical Sciences

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Section: Immunotherapy In Asthmamentioning

confidence: 99%

An Overview and Update on Asthma and its Management

Rajanandh¹

2015

J. of Medical Sciences

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“…A limited number of AIT studies performed in Europe with extracts of Cladosporium and Alternaria have demonstrated therapeutic efficacy [15]. Cochrane reviews included just 2 out of 88 AIT trials with Cladosporium in its meta-analysis [29][30][31]. There has been acceptable evidence showing Alternaria SCIT is beneficial in allergic children and improves medication scores, combined symptom-medication scores, and quality of life in the patients [32].…”

Section: Limitations To Immunotherapymentioning

confidence: 99%

Mold Allergy, Its Prevention and Therapy - Part 2

Özdemir¹

2015

MOJI

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In the current treatment of mold allergy, there are two modalities: Preventive and therapeutic approaches. Preventive approaches include measurements against indoor as well as outdoor molds. Relative humidity is suggested to maintain at <50% indoor environments. Windows are kept closed in warm months and air-conditioning ought to be used. Indoor plants, as a possible cause of allergen, should be exposed to direct sunlight from time to time.Visible molds are cleaned and mold-infested resources are should be discarded from houses. Washable surfaces must be cleaned with 5% bleach and detergent solution. Damp carpets are ought to dried out quickly and to think taking them away if humidity is not immediately goes away. In bathrooms, curtains and tile should be regularly checked and mended to keep waterproof. Firewood or newspaper piles or old books are regularly scrutinized and thrown away as necessary. Drip pans for fridges, garages and basements at homes should be regularly checked and cleaned. Water leaks in dwellings should be fixed swiftly.In outdoor environment, intense exposure to moldy plants must be avoided. A well-fitted particulate mask when functioning with moldy objects ought to be used. Air-conditioned vehicles should be utilized. Therapeutic approaches mentioned here for fungal allergy is specifically mold allergen immunotherapy in addition to pharmacotherapy against the effects of mold allergy. Mold allergen immunotherapy, as a specific therapy of fungal allergy, is previously hindered by the poor quality of most of the commercial extracts. There have been only several studies evaluating the efficacy of allergen immunotherapy with Alternaria extracts in patients with respiratory mold allergy.A meta-analysis demonstrated that clinical efficacy of allergen immunotherapy with mold extracts was revealed in 79 actively treated cases in 4 controlled trials, with only 2 mold species, namely Alternaria alternate and Cladosporium herbarium. Recently the American Academy of Allergy, Asthma & Immunology concluded that immunotherapy might be effective for mold allergy. In near future, diagnosis and therapy for mold allergy will be more decisive and effective with newly developed production techniques and methods.

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“…Allergen specific immunotherapy is effective and well tolerated treatment for allergic diseases. Allergen specific immunotherapy modifies the immunological response to allergens and induce a state of clinical tolerance [28][29][30]. SCIT was a safe treatment with a low risk to elicit severe systemic reaction, in which no fatality was observed.…”

Section: Diagnosis and Treatmentmentioning

confidence: 99%

A Brief Review on Immune Mediated Diseases

Adapa¹,

YRKM²,

Sy³

et al. 2011

J Clin Cell Immunol

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The immune system of an organism protects against disease by identifying and killing pathogens and tumor cells. But sometimes it may over-react or start attacking the body and results in immune-mediated diseases. Autoimmune diseases like allergic diseases, Sinusitis, atopic dermatitis, allergic asthma, idiopathic dilated cardiomyopathy, rheumatoid arthritis and some HIV associated diseases are part of immune mediated diseases. In this review we highlight some of the immune mediated diseases along with their diagnostic methods and therapeutic approaches.

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Allergen immunotherapy for asthma

Cited by 325 publications

References 172 publications

An Overview and Update on Asthma and its Management

An Overview and Update on Asthma and its Management

Mold Allergy, Its Prevention and Therapy - Part 2

A Brief Review on Immune Mediated Diseases

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