Allergenic materials in the house dust of allergy clinic patients

Barnes, Charles S.; Tuck, Janna; Simon, S.D.; Pacheco, Freddy; Hu, Frank B.; Portnoy, Jay M.

doi:10.1016/s1081-1206(10)62899-2

Cited by 43 publications

(20 citation statements)

References 22 publications

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“…15 , 16 , 18 , 19 Because of the complexity of fungal exposure assessment, few studies have assessed exposure to Alternaria or other fungal allergens in indoor environments. 20 Fungal allergen extracts have largely remained uncharacterized and non-standardized, unlike other common allergens derived from cat, dog, dust mite, cockroach, or pollens. 21 , 22 Exposure to fungal allergens is traditionally estimated by indirect methods, considering spores as indicators of the presence of allergens.…”

Section: Introductionmentioning

confidence: 99%

Dustborne Alternaria alternata antigens in US homes: Results from the National Survey of Lead and Allergens in Housing

Salo

Yin²,

Arbes

et al. 2005

Journal of Allergy and Clinical Immunology

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Section: Introductionmentioning

confidence: 99%

Dustborne Alternaria alternata antigens in US homes: Results from the National Survey of Lead and Allergens in Housing

Salo

Yin²,

Arbes

et al. 2005

Journal of Allergy and Clinical Immunology

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“…The abundance of conidia in the atmosphere is due in a large part to their ability to exist and thrive on a wide array of substrates. A number of studies have confirmed that Cladosporium spores are an important aeroallergen and exposure to high concentrations affects human health by increasing the incidence of asthma and bronchial ailments (Lewis et al 2000; Barnes et al 2001). Cladosporium has relatively small spores and so airborne concentrations must reach high levels in order to induce allergenic symptoms (Brown and Jackson 1978).…”

Section: Introductionmentioning

confidence: 99%

Relationships between airborne fungal spore concentration of Cladosporium and the summer climate at two sites in Britain

Hollins

Kettlewell

Atkinson

et al. 2004

International Journal of Biometeorology

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Cladosporium conidia have been shown to be important aeroallergens in many regions throughout the world, but annual spore concentrations vary considerably between years. Understanding these annual fluctuations may be of value in the clinical management of allergies. This study investigates the number of days in summer when spore concentration exceeds the allergenic threshold in relation to regional temperature and precipitation at two sites in England and Wales over 27 years. Results indicate that number of days in summer when the Cladosporium spores are above the allergenic concentration is positively correlated with regional temperature and negatively correlated with precipitation for both sites over the study period. Further analysis used a winter North Atlantic Oscillation index to explore the potential for long-range forecasting of the aeroallergen. For both spore measurement sites, a positive correlation exists between the winter North Atlantic Oscillation index and the number of days in summer above the allergenic threshold for Cladosporium spore concentration.

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“…9,10 A alternata, a cosmopolitan saprophyte commonly found in soil and plants, is usually considered an outdoor allergen. 1,11,12 Although most intense exposure is likely to occur outdoors, Alternaria and other allergenic fungi are also found in indoor environments.…”

mentioning

confidence: 99%