Allergic contact stomatitis due to desensitizing toothpastes

Abstract

Toothpastes are one of the most common personal care products among people of all ages. The various toothpaste types and their complex ingredients could cause irritation or allergic reactions. Allergic contact stomatitis has been often seen in clinical practice; however, desensitizing toothpastes as a trigger are often unrecognized. Here, we report three cases of allergic contact stomatitis due to stannous chloride‐containing desensitizing toothpastes. General dentists and other professionals should pay more attention to the safety and adverse effects of toothpastes.

Recurrent allergic contact stomatitis and aphtosis, without cheilitis, due to stannous (tin)‐containing toothpastes

“…Seven cases of allergic contact cheilitis due to stannous (tin) salts in dental products have been reported so far in the scientific literature. [2][3][4][5] In our previously published case 3 also aphtosis was part of the clinical picture, yet in that patient associated to a clear cheilitis. In the present case the solitary mucosal involvement, without any concomitant cutaneous lesions, is remarkable, because often the reverse occurs, that is, cutaneous rather than mucosal involvement, as the latter is believed to exhibit a higher level of tolerance.…”

“…Seven cases of allergic contact cheilitis due to stannous (tin) salts in dental products have been reported so far in the scientific literature 2–5 . In our previously published case 3 also aphtosis was part of the clinical picture, yet in that patient associated to a clear cheilitis.…”

“…Dental consumer products are an important cause of allergic contact cheilitis, 1 and stannous (tin) has been occasionally reported as a relevant culprit allergen in this regard. [2][3][4][5] We here present a patient with a delayed diagnosis of allergic contact stomatitis with aphtosis, but without cheilitis, due to tin-containing toothpastes.…”

Reações de contato causadas por dentifrícios - Relato de casos e revisão da literatura

“…Um outro composto relacionado a reações alérgicas é o estanho, presente em diferentes marcas de dentifrícios (Berton et al, 2017;He et al, 2022;Toma et al, 2018). Alguns produtos com fluoreto estanhoso têm, na sua formulação, concentração muito pequena de água (até 1%), o que pode contribuir para as reações de contato (Van Amerongen et al, 2020).…”