Allergic disease management in the elderly: a wakeup call for the allergy community

Montanaro, Anthony

doi:10.1016/s1081-1206(10)62442-8

Cited by 9 publications

(5 citation statements)

References 4 publications

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“…Under this condition, they inhale spores in large quantities into the upper and lower respiratory tract were the fungi establishes and grow to cause disease (Grewal et al, 1990;Manning and Holman, 1998). While in the older age the infection occur due to a defect in the immune system especially those who suffer from chronic diseases, who are taking immunosuppressive drugs and due to physiological changes such as dryness of mucous membranes lining the nose (which extends to the sinuses) with advancing age and thus increasing the possibility of the transmission of infection from the nose to the sinuses (Gungor and Adusumilli, 1998;Montanaro, 2000;Prateek et al, 2013). The fungi Penicillium spp.…”

Section: Discussionmentioning

confidence: 99%

In vitro antifungal effect of potassium sorbate and sodium benzoate on the growth of fungi causing sinusitis

Alsudani¹

2017

Afr. J. Microbiol. Res.

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The study involved 70 nasal swab collected from people suffering from sinusitis and consulted the Ear, Nose and Throat Unit in Al-Diwaniya Teaching Hospital, Iraq during the period from 12 June to 12 August 2016 with ages ranging from 0-65 years old. The results showed that the number of nasal swabs that gave fungal growth was 36/70 (51.428%); highest percentage of fungal infection was recorded in ages ranging from 11-20 years old 8(80%), followed by above 60 years old 7(70%) and lowest infection was in 51-60 years old 3(30%) when compared. A total of 43 fungal isolates were identified and the isolates belong to 7 genera comprising of Penicillium spp. with 16 isolates, Aspergillus spp. with 14 isolates (mainly A. niger= 7, A. flavus= 5 and A. fumigates= 2), Cladosporium spp. with 4 isolates, Rhizopus spp. 3 isolates, Sporothrix schenckii 3 isolates, Mucor spp. 2 isolates and Fusarium spp. 1 isolate. Penicillium spp. occurred with the highest frequency percentage of (37.209%), followed by A. niger (16.279%) and A. flavus (11.627%) with significant differences when compared with other fungi isolated in this study while the lowest percentage frequency was recorded for Fusarium spp. (2.325%). Potassium sorbate and Sodium benzoate have high inhibitory activity against the growth of all fungi studied and increases in their concentration caused corresponding increases in their percentage inhibition of fungal growth which ranged at concentration 1000 mg/L of potassium sorbate and sodium benzoate between (90.7-94.5%) and (91.2-95.8%) respectively.

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Section: Discussionmentioning

confidence: 99%

In vitro antifungal effect of potassium sorbate and sodium benzoate on the growth of fungi causing sinusitis

Alsudani¹

2017

Afr. J. Microbiol. Res.

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“…This might prompt an underestimation of cases, resulting in underdiagnosis and missing therapeutic intervention in this group. 7,8 Furthermore, the diagnosis of food allergy is complex because different immunologic mechanisms, IgE-mediated, cell mediated, or mixed causes, may play a role. 6 A few studies have explicitly addressed subchapters of food allergy, such as eosinophilic esophagitis or urticaria, in the elderly population.…”

Section: Prevalence Of Food Allergies In the Elderly Populationmentioning

confidence: 99%

Food allergies in the elderly

Jensen‐Jarolim

Jensen

2016

Annals of Allergy, Asthma & Immunology

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The population of elderly people in the European Union currently ranges from 12.2% (Ireland) to 20.6% (Germany). 1 Germany, with 17 million elderly people, thus currently represents the European country with the oldest population, and this cohort will increase to approximately 23.4 million by 2050. 1 According to the US Census Bureau, 2 in the United States approximately 47 million (15%) of the population are currently older than 65 years. It is moreover expected that the US population will become significantly older and reach 83.7 million people older than 65 years in 2050 (ie, 20% of the population). Notably, similar trends are expected in this report for all industrial countries. In all instances, the proportion of people older than 85 years will also significantly increase. From this, it can be expected that the new situation will challenge policymakers and health care professionals. In parallel with these changes, we may expect that the occurrence of allergies will also increase in the elderly cohort, especially considering environmental challenges.

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“…It is a matter of debate how much structural as well as functional changes of the mucosa and skin, in addition to immunological alterations affecting, for example, lymphocytes and lymphokines, encountered at old age are responsible for these figures [21][22][23] . Adverse reactions to food may differ in their pathophysiology encompassing both allergic and non-allergic hypersensitivity reactions [9] .…”

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confidence: 99%

Food Allergy: An Increasing Problem for the Elderly

Möhrenschlager

Ring

2010

Gerontology

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As populations become older all over the world, allergic reactions in elderly persons will be encountered more often in the future. Up to now, there has been much more literature on allergy prevalence in childhood than on allergy diseases in adults. As a challenge to epidemiology, allergic disorders in elderly persons may be masked by various symptoms corresponding with a general age-induced decline of physiological functions, including vitamin D deficiency and gastric pH increase. How much structural and functional changes (e.g. low calcitriol level) or effects caused by drugs (e.g. acid-suppression medications) in addition to immunological alterations encountered at old age are responsible for this development is a matter of debate. In the years ahead, the problem of allergy in adulthood and especially in the elderly will become more pronounced.

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Allergic disease management in the elderly: a wakeup call for the allergy community

Cited by 9 publications

References 4 publications

In vitro antifungal effect of potassium sorbate and sodium benzoate on the growth of fungi causing sinusitis

In vitro antifungal effect of potassium sorbate and sodium benzoate on the growth of fungi causing sinusitis

Food allergies in the elderly

Food Allergy: An Increasing Problem for the Elderly

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