Allergic reaction to Buscopan

Effects of Spascupreel versus hyoscine butylbromide for gastrointestinal cramps in children

“…On a four‐graded scale (‘very good’, ‘good’, ‘moderate’ and ‘low’), 2% of patients in the Spascupreel group and <1% in the control group reported less than ‘good’ tolerability. There are reports that scopolamine‐containing treatments may cause dry mouth, urinary retention and increases in ocular pressure 10,11 . These reports could not be substantiated in the current study.…”

“…The effects of orally administered hyoscine butylbromide on gastric motility were documented as early as in 1968 9 . However, hyoscine (scopolamine)‐containing treatments are associated, although infrequently, with dry mouth, urinary retention and increases in ocular pressure 10,11 …”

Antiperistaltic effect and safety of l-menthol sprayed on the gastric mucosa for upper GI endoscopy: a phase III, multicenter, randomized, double-blind, placebo-controlled study

“…8,9 Hyoscine-Nbutylbromide is associated with cardiovascular events, and glucagon can lead to delayed hypoglycemia. 10,11 Hyoscine-N-butylbromide also adversely affects the ocular, urinary, and salivary systems 11 and can cause allergic symptoms 12,13 and potentially fatal anaphylactic shock. 14 Glucagon can induce nausea and vomiting, as well as anaphylactic and allergic reactions.…”

Near-fatal outcome after administration of hyoscine-N-butylbromide (Buscopan®)

“…According to the South African Medical Association guidelines, a continuous ECG monitor is only necessary during conscious sedation if the patient has some cardiac problem. 5 The patient was a young healthy adult.…”

“…[1][2][3][4][5] This case is of special interest due to the complicated differential diagnosis. Hyoscine-N-butylbromide is frequently used for gastrointestinal spasm.…”