Allergy to peanuts in atopic dermatitis patients 14 year or older and the association with food hypersensitivity, inhalant allergens, asthma bronchiale and rhinitis

Abstract

Background:In adult patients suffering from atopic dermatitis (AD), studies investigating the co-prevalence of AD and food allergy are still scarce, and exact data are not available.Aims and Objectives:To evaluate the occurrence of food allergy to peanuts in significant relation to food hypersensitivity, inhalant allergy and to asthma bronchial and rhinitis.Materials and Methods:Altogether 332 patients of AD 14 year or older were included in the study. The complete dermatological and allergological examinations were performed in all included patients (including examination of specific immunoglobulin E, skin prick test to different food and inhalant allergens, anamnestic data about food reactions, evaluation of allergic rhinitis, and allergic asthma bronchiale). We evaluated whether there was some relation between the food allergy to peanuts and followed parameters. Pairs of these categories were entered in the contingency tables, and the Chi-square test for the relationship of these variables was performed with the level of significance set to 5%.Results:Altogether 332 persons suffering from AD were included in the study of which 120 were male and 212 were female; the average age was 27.2 year. The significant relation between the allergy to peanuts and the occurrence of food hypersensitivity (FH) reactions to tomatoes, kiwi, apples, oranges, carrot and to the sensitization to grass, trees, mites, and the occurrence of rhinitis was found.Conclusion:The significant relation between the allergy to peanuts and the occurrence of FH reactions and the sensitization to inhalant allergens and rhinitis was found. The future studies may show if the decrease in food allergy to peanuts can lead to the decrease of the occurrence of other FH reactions and sensitization to inhalant allergens and rhinitis in AD patients.

Atopic dermatitis, inhalant allergy and food allergy: A paediatric approach

“…Celakovska et al 14 Alternaria in their pediatric patients with AD. 11 Aktas et al worked on children with AD, and they determined aeroallergen sensitization in 46.4% of their patients.…”

“…Celakovska et al 14 worked on 332 (120 males and 212 females) AD patients. These authors noted that 61.1% (n = 203) of their patients were sensitized to mites, 47.6% (n = 158) were sensitized to animal dander, 14.2% (n = 47) to bird feather and 24.7% (n = 82) to dust, 50.3% (167) to mixture of trees and 67.8% (225) to mixture of grasses 14 .…”

“…Celakovska et al 14 worked on 332 (120 males and 212 females) AD patients. These authors noted that 61.1% (n = 203) of their patients were sensitized to mites, 47.6% (n = 158) were sensitized to animal dander, 14.2% (n = 47) to bird feather and 24.7% (n = 82) to dust, 50.3% (167) to mixture of trees and 67.8% (225) to mixture of grasses 14 . Seo et al reported that they detected inhalant sensitization to D. pteronyssinus , D. farinae , cat dander, dog dander, cockroach, and Alternaria in their pediatric patients with AD 11 .…”

Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components

“…ImmunoCAP ISAC (Thermo Fisher), based on 112 different molecular components (both extracted and recombinant), is the most studied and most frequently used molecular diagnostic tool based on a microarray (Melioli et al, 2011). In our previous studies, we evaluated the occurrence of sensitization to food and inhallant allergens in patients suffering from AD; these patients were subjected to skin prick test, atopy patch tests and extract specific IgE to different food and inhalant allergens (Čelakovská et al, 2014;Čelakovská et al, 2015;Čelakovská et al, 2018;Čelakovská & Bukač, 2017).…”

Cross-reactivity of sIgE to mite and shrimp induced allergies in different age groups and clinical profiles of shrimp sIgE in vegetarians

“…Food allergens can induce symptoms, such as rhinitis, urticaria, and anaphylaxis in patients 10 . The prevalence and types of food allergy vary according to age, local diet, and genes, and are triggered by various allergens sources, such as milk, eggs, peanuts, fish, and shellfish 11,12 . Shellfish, including crustaceans and molluscs, cause the most food allergies in both children and adults worldwide.…”