Allogeneic ABO-Mismatched Blood for Transfusion of Cold Antibody Autoimmune Hemolytic Anemia: A Case Report and Literature Review

Abstract

Autoimmune hemolytic anemia (AIHA) is defined as the increased destruction of red blood cells (RBCs) in the presence of anti-RBC autoantibodies and/or complement.Here in, we describe the case of a 52-year-old male patient who was admitted to our hospital, and was diagnosed with non-Hodgkin peripheral T-cell lymphoma and cold antibody autoimmune hemolytic anemia (extremely severe). He's hemoglobin decreased progressively after he was admitted, and he developed dyspnea. He also had continuous abdominal discomfort with nausea lasting 20 days. The patient reported abdominal discomfort with no obvious cause starting 20 days before admission, with nausea, vomiting, and poor appetite. In this case report we describe a case of a 52year-old male patient who had allogeneic ABOmismatched blood for transfusion of cold antibody autoimmune hemolytic anemia.