Allografts in der Rekonstruktion von kn�chernen Defekten bei prim�r malignen Knochentumoren

Wuisman, P.; Gohlke, Frank; Witlox, Adhiambo M.

doi:10.1007/s00132-003-0580-5

Cited by 8 publications

(5 citation statements)

References 43 publications

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“…Therefore mantle grafts are frequently used in the lower extremity [34–36] but require a bone bank for matching allografts. Postoperative complications include fractures, nonunions, and infections [2, 13–15, 36, 37]. Current available data show that mantle grafts provide a higher primary stability compared to bilateral fibular grafts [14, 15].…”

Section: Discussionmentioning

confidence: 99%

“…More than 80% of patients can receive limb-sparing resection [1–4] without having an increased risk of local recurrence. The spectrum of reconstruction possibilities is extensive with options as tumor arthroplasty [3, 5–7], massive allografts [8–13], mantle grafts (massive allograft combined with a vascularized fibular graft [2, 14, 15] or irradiated autograft combined with a vascularized fibular graft [16–18]), and biological methods such as fibular grafts (vascularized/nonvascularized, unilateral/bilateral, “double barrel fibula”) [4, 19–28], tibial flake, pelvis flake, and callus distraction [12, 29, 30]. …”

Section: Introductionmentioning

confidence: 99%

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Bilateral Fibular Graft: Biological Reconstruction after Resection of Primary Malignant Bone Tumors of the Lower Limb

Niethard

Tiedke

Andreou

et al. 2013

Sarcoma

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This paper deals with bilateral vascularized fibular grafts (BVFG) as a method for reconstruction of metadiaphyseal defects of the femur and tibia in young patients suffering from malignant bone tumors of the lower limb. This reconstructional technique was used in 11 patients undergoing metadiaphyseal resection of lower limb malignant bone tumors. All patients with Ewing's sarcoma and osteosarcoma had multimodal treatment according to the EURO-E.W.I.N.G 99 or COSS-96 protocol. Median FU was 63 months. None of the patients experienced local recurrence during FU. 2 patients died due to distant disease during FU. Full weight- bearing was permitted after a mean of 8 months. The median MSTS score was 87%. Complications occurred in five patients. None of the complications led to failure of the biological reconstruction or to amputation. Biological reconstruction of osseous defects is always desirable when possible and aims at a permanent solution. Good functional and durable results can be obtained by using BVFG for the reconstruction of metadiaphyseal defects of the femur and tibia. Radiotherapy in the multimodal setting increases the risk for graft or fixation failure.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bilateral Fibular Graft: Biological Reconstruction after Resection of Primary Malignant Bone Tumors of the Lower Limb

Niethard

Tiedke

Andreou

et al. 2013

Sarcoma

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“…For instance these grafts have a lower technical demand for the surgeon and can reduce donor-site complications. 38,39 Several recent studies have shown that FNFAs harvested by a minimally invasive technique had the same benefits as FNFAs harvested by the periosteum-preserving technique in the treatment of bone defects in children and adults. [40][41][42] In the above-mentioned studies, complete regeneration of the donor site after FNFA harvesting was obtained in most patients.…”

Section: Discussionmentioning

confidence: 99%

Treatment of tumor-like lesions in the femoral neck using free nonvascularized fibular autografts in pediatric patients before epiphyseal closure

et al. 2018

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Objectives Surgical resection of benign bone tumors and tumor-like lesions at the femoral neck presents a difficult reconstructive challenge. However, the safety and efficacy of free nonvascularized fibular autografts (FNFAs) in the treatment of femoral neck tumor-like lesions before epiphyseal closure in young patients remain unknown. Methods Sixteen pediatric patients who had not yet undergone epiphyseal closure were treated with FNFAs after resection of tumor-like lesions in the femoral neck from August 2012 to September 2016. All patients underwent supplementary skeletal traction through the supracondylar femur for 4 to 6 weeks after resection. Demographic data were recorded and clinical and radiological outcomes were evaluated during the follow-up. Results All patients could walk with partial weight bearing 4 weeks postoperative, and full weight bearing was permitted after a mean of 8 weeks. Graft union was attained in all 16 patients at a mean of 2 months. The donor site of the fibular cortical strut showed good regeneration in all patients. The Harris hip score significantly improved from 65% to 95%. Conclusions Application of an FNFA is a feasible method in the treatment of tumor-like lesions in the femoral neck before epiphyseal closure in pediatric patients. Level of Evidence Level IV.

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“…Common fillers include autogenous bone, allogeneic bone, artificial bone, artificial prosthesis, bone cement, etc. The author adopts autologous or cancellous allogenic bone and imported Austine replacement bone aiming at small bone defect; massive allogeneic bone is adopted aiming at big bone defect [ 1]; hemiarthrosis is adopted for cases with young age aiming at malignant tumor around knee joint, older cases undergo artificial prosthesis replacement [ 2]. Therefore, it can be concluded that allogeneic bone at least still occupy an important position in bone defect filler till present.…”

Section: Position Of Allogeneic Bone In Bone Defect Fillersmentioning

confidence: 99%

Application of allograft bone transplantation in bone tumour surgery

Jiang¹,

Zhang²,

Wu³

et al. 2018

Proceedings of the 2018 International Conference on Advances in Social Sciences and Sustainable Development (ASSSD 2018)

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Objective: To discuss the scope, effect, rejection reaction, etc. of applying allograft bone transplantation in bone tumour surgery. Method: 120 cases of allogeneic bone transplantation were used in bone tumour surgery from October 1983 to March 2003, including 102 cases of tumor curettage and cancellous allogenic bone transplantation; 12 cases of tumor curettage, allograft massive cortical bone and cancellous bone transplantation; 2 cases of bone tumor segmental resection and allograft femoral shaft transplantation; 3 cases of bone tumor segmental resection and hemiarthrosis transplantation and 1 case of tumor excision and massive allograft sacrum transplantation. Results: 2 of 120 cases had minor rejection reaction only, who were mostly manifested as post-operative incision exudation, exudation was stopped and the incision was healed three months later, incision, and other cases are healed by the first intention. Conclusion: allograft bone has wide application scope, excellent effect and rare rejection reaction in bone tumour surgery. It is important in bone defect fillers. Currently, bone defect fillers are more and more. Common fillers include autogenous bone, allogeneic bone, artificial bone, artificial prosthesis, bone cement, etc. What is the position of allogeneic bone among various bone defect fillers? How about application scope, effect, rejection reaction, etc. in bone tumour surgery especially? In the paper, 120 cases of allogeneic bone transplantation in our department from October 1983 to March 2003 are summarized. The above issues are discussed.

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Allografts in der Rekonstruktion von kn�chernen Defekten bei prim�r malignen Knochentumoren

Cited by 8 publications

References 43 publications

Bilateral Fibular Graft: Biological Reconstruction after Resection of Primary Malignant Bone Tumors of the Lower Limb

Bilateral Fibular Graft: Biological Reconstruction after Resection of Primary Malignant Bone Tumors of the Lower Limb

Treatment of tumor-like lesions in the femoral neck using free nonvascularized fibular autografts in pediatric patients before epiphyseal closure

Application of allograft bone transplantation in bone tumour surgery

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