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Cho, YS; Jw, Lee; Jh, Lee; Tr, Yoon; Kuroyanagi, Y; Park, Moon Ho; Dg, Pyun; Kim, Hyung Jun

doi:10.1023/a:1016500429225

Cited by 45 publications

(12 citation statements)

References 7 publications

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“…Drug occlusion into the pores of the support and stronger drug-framework silver ions interaction could be the reason for its extended release. This prolonged release of SD is similar to that of found on silver containing nanoporous silica materials [29], but much faster than on polymer based systems loaded with AgSD [39].…”

Section: Fig 1 Sem Images Of the Parent Hy (A) And Sd/hy(ss) (B) Sasupporting

confidence: 79%

Solid-state encapsulation of Ag and sulfadiazine on zeolite Y carrier

Mavrodinova

Popova

Yoncheva

et al. 2015

Journal of Colloid and Interface Science

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by Solid-state Ion Exchange (SSIE) procedure over zeolite Y, followed by deposition of sulfadiazine (SD) by dry mixing was examined for the preparation of topical antibacterial formulations. The ion-exchange and adsorptive properties of the zeolite matrix were utilized for the bactericidal Ag deposition and loading of antibiotic sulfadiazine.Experiments: Assessment of the encapsulation efficiency of both active components loaded by solid and liquid deposition methods was made by X-ray diffraction, TEM, FT-IR spectroscopy and thermogravimetric analysis (TGA). SD release kinetics was also determined.Findings: Sustained delivery of sulfadiazine has been observed from the Ag-modified zeolites compared to the parent HY material. It was found that if SD was loaded in solution, part of the zeolite silver ions was released and interacted with SD, forming AgSD. By solid-state SD deposition, the reaction between the drug and the silver was restricted within the limits of inter-atomic interaction, and total but prolonged drug release occurred.

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Section: Fig 1 Sem Images Of the Parent Hy (A) And Sd/hy(ss) (B) Sasupporting

confidence: 79%

Solid-state encapsulation of Ag and sulfadiazine on zeolite Y carrier

Mavrodinova

Popova

Yoncheva

et al. 2015

Journal of Colloid and Interface Science

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“…In comparison to organic antibiotic, silver ions are active against a broad spectrum of bacteria, viruses, and fungi, and the risk of resistance development is much lower. For these reasons, medical devices like catheters (18)(19)(20)(21)(22)(23)(24)(25), heart valve sewing cuffs (21,26,27), wound dressings (2,(28)(29)(30)(31)(32)(33), or sutures (21,34) are coated with elemental silver (2,21,26,27,30,31,33), silver sulfadiazine (18, 19, 21-23, 28-30, 33), silver ion containing hydrogels (21,25,33), or silver ion doped bioglasses (20,24,34) to minimize the risk of infection. The antimicrobial efficacy of coatings containing ionic silver or elemental silver nanoparticles was shown in many studies.…”

Section: Introductionmentioning

confidence: 99%

“…The water uptake of the polymer matrix appears to be a crucial factor for silver ion release. Additives improving the water uptake were shown to increase the silver ion release (29). .…”

Section: Introductionmentioning

confidence: 99%

Properties of Nanosilver Coatings on Polymethyl Methacrylate

2005

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A Elemental silver particles were prepared by the reduction of silver nitrate in ethanol in the presence of poly(N-vinyl-2-pyrrolidone), poly(N-vinyl-2-pyrrolidone)-co-polyvinyl acetate or poly(N-vinyl-2-pyrrolidone)-co-polyvinyl alcohol as stabilizing agent. Transmission electron microscopy (TEM) investigations reveal that in all cases spherical silver particles are obtained.Using poly(N-vinyl-2-pyrrolidone) or poly(N-vinyl-2-pyrrolidone)-co-polyvinyl alcohol as stabilizer, the average diameter of the silver particles is around 20 nm, and the degree of aggregation is low. That means these polymers are good stabilizers for silver particles. In contrast to that, in the presence of poly(N-vinyl-2-pyrrolidone)-co-polyvinyl acetate, heavily aggregated silver particles are formed.The good film-forming properties of the stabilizers were exploited to prepare coatings onto polymethylmethacrylate sheets using the silver dispersions.The optical as well as the silver ion release properties of the silver coatings were investigated. As expected, the wavelength of the surface plasmon resonance absorption shows a bathochromic shift with increasing mean diameter of the silver particles. The amount of silver ions released from these coatings as well as the kinetics of silver ion release depend on the polymer used as stabilizer for the silver particles. Silver ion diffusion processes govern the silver ion release kinetics from coatings consisting of silver nanoparticles and poly(N-vinyl-2-pyrrolidone) or poly(N-vinyl-2-pyrrolidone)-co-polyvinyl alcohol.

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“…Composite polyurethane foams impregnated with HA and silver sulfadiazine have been shown to reduce wound size significantly in an experimental rat model [277]. Another HA-based composite hydrogel for tissue repairing application is developed by either crosslinking of HA with glycidyl methacrylate groups and DNA [278], or functionalization of HA with thiol cross-linking sites [279].…”

Section: Biomaterials and Nanobiomaterials Used For Several Scaffomentioning

confidence: 99%

Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review

Chaudhari

Vig

Baganizi

et al. 2016

IJMS

466

288

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Over centuries, the field of regenerative skin tissue engineering has had several advancements to facilitate faster wound healing and thereby restoration of skin. Skin tissue regeneration is mainly based on the use of suitable scaffold matrices. There are several scaffold types, such as porous, fibrous, microsphere, hydrogel, composite and acellular, etc., with discrete advantages and disadvantages. These scaffolds are either made up of highly biocompatible natural biomaterials, such as collagen, chitosan, etc., or synthetic materials, such as polycaprolactone (PCL), and poly-ethylene-glycol (PEG), etc. Composite scaffolds, which are a combination of natural or synthetic biomaterials, are highly biocompatible with improved tensile strength for effective skin tissue regeneration. Appropriate knowledge of the properties, advantages and disadvantages of various biomaterials and scaffolds will accelerate the production of suitable scaffolds for skin tissue regeneration applications. At the same time, emphasis on some of the leading challenges in the field of skin tissue engineering, such as cell interaction with scaffolds, faster cellular proliferation/differentiation, and vascularization of engineered tissues, is inevitable. In this review, we discuss various types of scaffolding approaches and biomaterials used in the field of skin tissue engineering and more importantly their future prospects in skin tissue regeneration efforts.

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Untitled

Cited by 45 publications

References 7 publications

Solid-state encapsulation of Ag and sulfadiazine on zeolite Y carrier

Solid-state encapsulation of Ag and sulfadiazine on zeolite Y carrier

Properties of Nanosilver Coatings on Polymethyl Methacrylate

Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review

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