Fine-structure dynamics in solar prominences holds critical clues to understanding their physical nature of significant space-weather implications. We report evidence of rotational motions of horizontal helical threads in two activeregion prominences observed by the Hinode and/or IRIS satellites at high resolution. In the first event, we found transverse motions of brightening threads at speeds up to 55 km s −1 seen in the plane of the sky. Such motions appeared as sinusoidal space-time trajectories with a typical period of ∼390 s, which is consistent with plane-of-sky projections of rotational motions. Phase delays at different locations suggest propagation of twists along the threads at phase speeds of 90-270 km s −1 . At least 15 episodes of such motions occurred in two days, none associated with any eruption. For these episodes, the plane-of-sky speed is linearly correlated with the vertical travel distance, suggestive of a constant angular speed. In the second event, we found Doppler velocities of 30-40 km s −1 in opposite directions in the top and bottom portions of the prominence, comparable to the plane-of-sky speed. The moving threads have about twice broader line widths than stationary threads. These observations, when taken together, provide strong evidence for rotations of helical prominence threads, which were likely driven by unwinding twists triggered by magnetic reconnection between twisted prominence magnetic fields and ambient coronal fields.