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Catalytic Oxidative Processes in Steroid Chemistry: Allylic Oxidation, β-Selective Epoxidation, Alcohol Oxidation and Remote Functionalization Reactions

“…These include peroxyacetic acid and a catalytic amount of 2,4-dimethylpentane-2,4-diol cyclic chromate in 84% yield [180], dioxygen in the presence of ethyl 2-oxocyclopentanecarboxylate catalyzed by a cobalt(II) Schiff's base complex (Fig. 12) in 55% yield [181], BAIB as stoichiometric oxidant with catalytic amounts of TEMPO in 80% yield [171], CH 3 CN and CCl 4 with Mn(acac) 3 as catalyst in 80% yield [182], and N-chlorosuccinimide in the presence of K 2 CO 3 and MS 4Å with N-tert-butylbenzenesulfenamide as catalyst in 92% yield [165]. Allyl methyl carbonate and RuH 2 (PPh 3 ) 4 have been used for the same oxidation leading to 52% yield.…”