Alteraciones intestinales en pacientes con lesión medular

Vallès, Margarita; Mearin, Fermı́n

doi:10.1016/j.gastrohep.2011.11.014

Cited by 3 publications

(2 citation statements)

References 32 publications

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“…The neurological level is defined as the most distal segment of the spinal cord with normal motor and sensory function on both sides of the body, while the severity is defined as complete/incomplete sensory and incomplete motor with preserved function in more than a half of the key muscles or incomplete motor with preserved function in at least half of the key muscles [49]. For example, those patients injured in segments C6-C8 will require additional care to avoid comorbidities caused by BD or neurogenic bladder (NB) [50].…”

Section: How Could Bd In Sci Patients Be Explained?mentioning

confidence: 99%

Beyond the Quality of Life in Bowel Dysfunction after Spinal Cord Injury: Approaches to the Consequences in Motility, Immune System, and Microbiome

Cruz-Castillo¹,

García-Vences²

2021

Paraplegia

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Spinal cord injury (SCI) is a harmful event that involves several repercussions on sensory and motor function that affects the quality of life (QoL) of patients. After SCI, many damage mechanisms are activated that impact on both autonomous extrinsic and intrinsic innervation toward the gut, and these changes modify the gut motility causing bowel dysfunction (BD), an entity that affects 40% of patients with SCI, being the second comorbidity after loss of mobility with no recognized cure. The severity of complications is ruled by the level and severity of injury, having a worse prognosis with an injury that is the most proximal to the brain. In the last 5 years, some experiments have tried to elucidate the consequences of dysbiosis in the gut and aggregated proinflammatory processes. The goal of this chapter is to establish the importance of bacterial composition and immune system repercussions in bowel dysfunction after SCI and how could it give rise to new therapies.

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Section: How Could Bd In Sci Patients Be Explained?mentioning

confidence: 99%

Beyond the Quality of Life in Bowel Dysfunction after Spinal Cord Injury: Approaches to the Consequences in Motility, Immune System, and Microbiome

Cruz-Castillo¹,

García-Vences²

2021

Paraplegia

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“…La presencia de alteraciones gastrointestinales tiene una relación estadísticamente significativa con el tipo de lesión según afectación de miembros y según extensión. Esto concuerda con la opinión de Vallès (134), que explica que la fisiopatología de la Según el estudio de Haisma (23), las personas con tetraplejia y con lesión incompleta presentan más dolor musculoesquelético. En el estudio de Burke (137), el dolor neuropático es más común en pacientes con tetraplejia, tras un año después de la lesión y en pacientes mayores.…”

Section: Complicaciones Gastrointestinalesunclassified