Alteration of Retinal Vessel Diameter of the Patients with Pseudoexfoliation and Optical Coherence Tomography Images

Oruc, Yavuz; Kirgiz, Ahmet

doi:10.1080/02713683.2019.1632351

Cited by 6 publications

(1 citation statement)

References 17 publications

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“…In a previous meta-analysis, Wang et al [44] showed that PEX increases the risk of vascular disease, coronary heart disease, cerebrovascular disease, and aortic aneurysm compared with the control group. Moreover, the narrowing of the small vessels in the PEX eye in a unilateral PEX was observed in some studies [45,46]. Yuksel et al [47] found a significantly thinner RNFL in the PEX eye in a unilateral PEX without glaucoma, which suggested that an ocular blood flow disturbance through PEX deposition might contribute to the development of inner retinal atrophy.…”

Section: Discussionmentioning

confidence: 97%

The Differences in the Pattern of OCT and OCTA Examinations between Early Normal- and High-Tension Pseudoexfoliative Glaucoma

Łukasik

Wróbel-Dudzińska

Jarecki

et al. 2023

JCM

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Purpose. The aim of this study was to compare the results of optical coherence tomography angiography (OCTA) and optical coherence tomography (OCT) examinations in patients with normal-tension glaucoma (NTG) in comparison to high-tension pseudoexfoliative glaucoma (HTG) patients at the early stage of glaucoma. Material and methods. The studied groups consisted of patients in the early stage of NTG (70 eyes) and the early stage of HTG (71 eyes). In NTG and HTG groups, a detailed ophthalmic examination was performed. Optic disc OCT with peripapillary RNFL measurements and OCTA examination with the evaluation of the macula and optic disc were performed for all participants using Zeiss Cirrus 5000. Results. NTG and HTG groups were statistically similar as far as the MD was concerned, and both groups had early glaucoma. When evaluating the RNFL thickness, the only statistical difference between early NTG and HTG was observed in the thicknesses in the temporal sector of peripapillary RNFL, with thinner values in the NTG group (53.94 vs. 59.94, p = 0.0071). When the OCTA results of the macula and optic disc were evaluated, there were no statistical differences between early NTG and HTG. Conclusions. The vascular density and flow parameters assessed in OCTA were equal between early NTG and HTG, and therefore the involvement of vascular factors in NTG pathogenesis could not be confirmed. Our results confirm the preponderance of more frequent temporal RNFL involvement in early NTG.

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