Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure

Khalil, Fatma; Kang, Ik Joon; Undap, Suzanne L.; Tasmin, Rumana; Qiu, Xuchun; Shimasaki, Yohei; Oshima, Yuji

doi:10.1016/j.chemosphere.2013.02.042

Cited by 52 publications

(20 citation statements)

References 37 publications

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“…Oruç (2010) found the 96-h LC50 of chlorpyrifos for adult nile tilapia (Oreochromis niloticus) as 154 µg/L, which is about five times lower than we reported for Banded Gourami. Almost similar LC50 values of chlorpyrifos for different fish were estimated by earlier studies (Sharbidre et al, 2011;Mhadhbi and Beiras, 2012;Khalil et al, 2013). Rao et al (2003) found much more lower short-term LC50 of chlorpyrifos for…”

Section: Effects Of Chlorpyrifos On the Mortality Of Banded Gouramisupporting

confidence: 71%

Effects of insecticides on aquatic ecosystems in Bangladesh

Sumon

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Section: Effects Of Chlorpyrifos On the Mortality Of Banded Gouramisupporting

confidence: 71%

Effects of insecticides on aquatic ecosystems in Bangladesh

Sumon

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“…The effects of chlorpyrifos on rainbow trout brain have been scarcely studied, despite these being extensively reported in other fish species (Xing et al 2010;Yen et al 2011;Khalil et al 2013;Mishra & Devi 2014). For example, Xing et al (2010) indicated that chlorpyrifos induced AChE inhibition in the brain of common carp.…”

Section: Discussionmentioning

confidence: 99%

“…For example, Xing et al (2010) indicated that chlorpyrifos induced AChE inhibition in the brain of common carp. In another study, chlorpyrifos caused a significant decrease in brain AChE activity in Oryzias latipes (Khalil et al 2013). Finally, Yen et al (2011) tested chlorpyrifos on larval zebrafish, observing an AChE inhibition in the fish brains.…”

Section: Discussionmentioning

confidence: 99%

Thein vitroandin vivoeffects of chlorpyrifos on acetylcholinesterase activity of rainbow trout brain

Topal

Şişecioğlu

Atamanalp

et al. 2015

Journal of Applied Animal Research

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Chlorpyrifos is widely used to control agricultural pests associated with fruit, nut and vegetable crops, despite its toxic effects and potential brain alterations in aquatic organisms. This study was carried out to determine the in vivo and in vitro effects of chlorpyrifos on rainbow trout brain acetylcholinesterase (AChE) enzyme activity. The fish were exposed to 2.25 µg/L (25% of 96 h LC 50 ), 4.5 µg/L (50% of 96 h LC 50 ) and 6.75 µg/L (75% of 96 h LC 50 ) of chlorpyrifos for 24, 48, 72 and 96 h. In vitro studies, inhibition constants (K i ) and half-maximal inhibitory concentration (IC 50 ) values for chlorpyrifos were determined by Lineweaver-Burk graphs and by plotting activity percentage vs.[I], respectively. Enzyme activities were determined by a colorimetric method. In fish exposed to chlorpyrifos 2.25 and 4.5 µg/L, enzyme inhibition was not observed (p > 0.05); however, chlorpyrifos exposure to 6.75 µg/L for 72 and 96 h caused a significant decrease in enzyme activity (p < 0.05). The IC 50 value of chlorpyrifos was found to be 30 µg/L. These results show that chlorpyrifos may cause direct cellular injury in the brain, and suggest that AChE may be used as a bioindicator for toxicological studies.

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“…(Kondo et al., 2009a; Saito and Tanaka, ; Kikuchi and Hamaguchi ; Liew and Orban )); (III) regulation of behavior including schooling (Engeszer et al., ; Wark et al., ; Miller and Gerlai ; Greenwood et al., ; Kowalko et al., ; Liew and Orban ), aggression (Norton et al., ; Ariyomo et al., ) and reproduction; (IV) teratology and environmental toxicology ( e.g . (Nakayama et al., ; Khalil et al., )); and lastly (V) immunity (Sullivan and Kim ; Rauta et al., ; Renshaw and Trede ). Such broad genetic analysis in laboratory models can then provide specific research models for diseases affecting both fish and humans.…”

Section: Expansion Of Analysismentioning

confidence: 99%

Fish is Fish: the use of experimental model species to reveal causes of skeletal diversity in evolution and disease

Henke

Hawkins

et al. 2014

J. Appl. Ichthyol.

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Summary Fishes are wonderfully diverse. This variety is a result of the ability of ray-finned fishes to adapt to a wide range of environments, and has made them more specious than the rest of vertebrates combined. With such diversity it is easy to dismiss comparisons between distantly related fishes in efforts to understand the biology of a particular fish species. However, shared ancestry and the conservation of developmental mechanisms, morphological features and physiology provide the ability to use comparative analyses between different organisms to understand mechanisms of development and physiology. The use of species that are amenable to experimental investigation provides tools to approach questions that would not be feasible in other ‘non-model’ organisms. For example, the use of small teleost fishes such as zebrafish and medaka has been powerful for analysis of gene function and mechanisms of disease in humans, including skeletal diseases. However, use of these fish to aid in understanding variation and disease in other fishes has been largely unexplored. This is especially evident in aquaculture research. Here we highlight the utility of these small laboratory fishes to study genetic and developmental factors that underlie skeletal malformations that occur under farming conditions. We highlight several areas in which model species can serve as a resource for identifying the causes of variation in economically important fish species as well as to assess strategies to alleviate the expression of the variant phenotypes in farmed fish. We focus on genetic causes of skeletal deformities in the zebrafish and medaka that closely resemble phenotypes observed both in farmed as well as natural populations of fishes.

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Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure

Cited by 52 publications

References 37 publications

Effects of insecticides on aquatic ecosystems in Bangladesh

Effects of insecticides on aquatic ecosystems in Bangladesh

Thein vitroandin vivoeffects of chlorpyrifos on acetylcholinesterase activity of rainbow trout brain

Fish is Fish: the use of experimental model species to reveal causes of skeletal diversity in evolution and disease

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