2022
DOI: 10.3389/fnins.2022.904468
|View full text |Cite
|
Sign up to set email alerts
|

Alterations of Cerebral Blood Flow and Its Connectivity in Olfactory-Related Brain Regions of Type 2 Diabetes Mellitus Patients

Abstract: To investigate the alteration of cerebral blood flow (CBF) and its connectivity patterns in olfactory-related regions of type 2 diabetes mellitus (T2DM) patients using arterial spin labeling (ASL). Sixty-nine patients with T2DM and 63 healthy controls (HCs) underwent ASL scanning using 3.0T magnetic resonance imaging. We compared the CBF values of the olfactory-related brain regions between the two groups and analyzed the correlation between their changes and clinical variables. We also used these regions as s… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2024
2024
2025
2025

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(1 citation statement)
references
References 48 publications
0
1
0
Order By: Relevance
“…In this study, compared with the HCs, there was extensive damage to the microstructure of the association fibers and CF in T2DM patients, consistent with previous study 37 . Hyperglycemia and broad impairment of microvascular function in T2DM patients will contribute to inflammatory and hypoperfusion, resulting in insufficient brain blood supply 38 , 39 . Brain is very sensitive to ischemia which could damage white matter fibers microstructural integrity 40 .…”
Section: Discussionmentioning
confidence: 99%
“…In this study, compared with the HCs, there was extensive damage to the microstructure of the association fibers and CF in T2DM patients, consistent with previous study 37 . Hyperglycemia and broad impairment of microvascular function in T2DM patients will contribute to inflammatory and hypoperfusion, resulting in insufficient brain blood supply 38 , 39 . Brain is very sensitive to ischemia which could damage white matter fibers microstructural integrity 40 .…”
Section: Discussionmentioning
confidence: 99%