Altered molecular dynamics and antioxidant status in the spermatozoa in testosterone-induced oligospermia in mouse

Toxic Interaction of Pyrethroid (Katron) and Sodium Fluoride on Reproductive Performance of Male Albino Rats

“…Nearly similar finding to our data that were obtained by salem et al (1996) who demonstrated that cypermethrin significantly decreased sperm motility, sperm cell concentration and percentage of live sperm and significantly increase incidence of sperm motilities compared with untreated controls Epididymal sperm count of male rat was decreased significantly after administration of sodium fluoride at a dose of 20 mg/kg/day for 29 days by oral gavage as mentioned by Ghosh, et al (2002). This significant decrease in sperm concentration may be attributed to the decrease in the testosterone levels, while the reduction in testosterone levels may be reduce the sperm cell counts by two mechanisms, the first through its direct effect on spermatogenesis and the second may be through elevation of super oxide anion and suppression of SOD activities (Purohit et al, 2000).…”

Influence of Season on the Freezability of Free‐Range Poultry Semen

“…Testosterone may affect sperm membrane properties, as reported in certain mammalian species (Ballesteros et al. 1983; Purohit et al. 2000), and differences in the toxic effect of cryoprotectants might be expected depending on the level of circulating hormones.…”

“…A lengthening photoperiod acts as an environmental cue, stimulating the secretion of FSH, LH and testosterone, which play important roles in spermatogenesis and semen production (Thurston and Korn 2000). Testosterone may affect sperm membrane properties, as reported in certain mammalian species (Ballesteros et al 1983;Purohit et al 2000), and differences in the toxic effect of cryoprotectants might be expected depending on the level of circulating hormones. The relationship between the concentrations of these hormones and cryopreservation success may be linear, unlike in certain mammalian species (Coloma et al 2010a).…”

Cistanche deserticola decoction alleviates the testicular toxicity induced by hydroxyurea in male mice

“…[10][11][12] However, supraphysiological doses of testosterone and its derivatives are known to suppress spermatogenesis. 13 Toxicology research has shown that the serum testosterone levels decreased to approximately 5.0-10.0 g crude drug kg 21 body weight of CD decoction in normal mice. 14 It is possible that the suppression effect of CD as an ectogenic androgen-like agent made the dose-dependent effect of the three doses of CD decoctions against testicular injury more difficult to detect.…”