Alternate current biosusceptometry for the assessment of gastric motility after proximal gastrectomy in rats: a feasibility study

Abstract

The ACB system was able to assess GE, OCT, and GC in gastrectomized rats. Overall, PG accelerated GE and gastrointestinal transit, likely due to the increase in both intragastric pressure and amplitude contraction. Our data presented an efficient model to investigate functional consequences from gastric surgeries that will allow further studies involving different procedures.

Real-time liver uptake and biodistribution of magnetic nanoparticles determined by AC biosusceptometry

“…3,26,34 Alternating current biosusceptometry (ACB) is a biomagnetic detection system, extensively employed in gastroenterology assessments in both animal and human studies. [35][36][37][38][39] The technique is relatively inexpensive, portable, and versatile, allowing noninvasive investigations of physiological patterns in vivo and in real time with quantitative analyses of magnetic nanoparticle (MNP) concentrations in samples. 40 In the present study, we used a joint ACB approach to evaluate dynamic MNP liver accumulation associated with MNP biodistribution patterns.…”

Mild diabetes: long‐term effects on gastric motility evaluated in rats

“…Our study explores the ACB as an alternative technique for long-term monitoring of gastric motor function with safety and reliability. Ultimately, the ACB technique is able to monitor contractility and transit on several GI segments, despite some limitations that can be overcome with the development of sensors designed specifically for experimental animals (Calabresi et al 2015). The alternate current biosusceptometry (ACB) system is a biomagnetic device that has already been validated for the evaluation of gastrointestinal motility in different animal models and humans (Americo et al 2007;Am erico et al 2010;Quini et al 2012).…”

Advanced analysis of magnetic nanoflower measurements to leverage their use in biomedicine

“…Because a lognormal distribution raised to any power remains lognormally distributed, it follows from these assumptions that both their size and relaxation time s B follow a lognormal distribution, described by eqn (16).…”

“…Among these techniques, Magnetic Particle Imaging (MPI) 8,9 is the most known and matured towards clinical applications such as vascular perfusion imaging, 10 stem cell tracking 11 and image-guided hyperthermia. 12 Nevertheless, other still-to-mature nanoparticle imaging techniques such as magnetorelaxometry imaging (MRXi) 13,14 and magnetic susceptibility imaging (MSI) 15,16 have a promising future ahead. It is also possible to increase the sensitivity and/or resolution of established diagnostic imaging techniques by indirectly measuring the impact of the particles' magnetic elds on the imaging signal.…”