Alternating versus synchronous ventilation of the two lungs

Versprille, A.; Jansen, Jos R. C.

doi:10.1007/978-94-011-5129-0_11

Physiology and Pharmacology of Cardio-Respiratory Control 1998

DOI: 10.1007/978-94-011-5129-0_11

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Alternating versus synchronous ventilation of the two lungs

A. Versprille¹,

Jos R. C. Jansen²

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1999

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The genetic mediation of individual differences in sensitivity to pain and its inhibition

Mogil

1999

Proc. Natl. Acad. Sci. U.S.A.

384

220

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The underlying bases of the considerable interindividual variability in pain-related traits are starting to be revealed. Although the relative importance of genes versus experience in human pain perception remains unclear, rodent populations display large and heritable differences in both nociceptive and analgesic sensitivity. The identification and characterization of particularly divergent populations provides a powerful initial step in the genetic analysis of pain, because these models can be exploited to identify genes contributing to the behavior-level variability. Ultimately, DNA sequence differences representing the differential alleles at pain-relevant genes can be identified. Thus, by using a combination of ''top-down'' and ''bottom-up'' strategies, we are now able to genetically dissect even complex biological traits like pain. The present review summarizes the current progress toward these ends in both humans and rodents.

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The genetic mediation of individual differences in sensitivity to pain and its inhibition

Mogil

1999

Proc. Natl. Acad. Sci. U.S.A.

384

220

View full text Add to dashboard Cite

show abstract

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Alternating versus synchronous ventilation of the two lungs

Cited by 1 publication

References 12 publications

The genetic mediation of individual differences in sensitivity to pain and its inhibition

The genetic mediation of individual differences in sensitivity to pain and its inhibition

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