Alternative Medicine: New Ways to Treat Diseases and Therapies

Mamidi, T. R.; Yamini, M; Cherukuri, V. S. P.; Yarraguntla, Srinivasa Rao

doi:10.36468/pharmaceutical-sciences.744

Cited by 5 publications

(6 citation statements)

References 36 publications

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“…Not much is known about the possible interactions of integrated-pathy with chemotherapy (CT), radiation therapy (RT), or biological therapies, as well as how these interactions relate to results [ 25 ]. The purpose of the current study was to find the efficacy of integrated-pathy among cancer patients undergoing treatment at Patanjali Yoggram, Haridwar, who were also receiving the best CAM treatments and conventional CTRT.…”

Section: Introductionmentioning

confidence: 99%

Impact assessment of integrated-pathy on cancer-related fatigue in cancer patients: an observational study

Balkrishna,

Katiyar,

Ghosh

et al. 2024

J Health Popul Nutr

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Background Integrated-pathy aims to integrate modern medicine with traditional systems via applying the holistic approach of Ayurveda, Yoga, and natural medicine. This is important for addressing the challenges surrounding the delivery of long-term palliative care for chronic ailments including cancer. The prime intent of this study was to substantiate the underlying hypothesis behind the differential and integrative approach having a positive impact on Quality of Life of cancer patients. Study design Cross-sectional Observational study. Methods A standardized questionnaire was developed and used, after obtaining written informed consent from patients to assess the impact of Integrated-pathy on patients (n = 103) diagnosed with cancer receiving care at Patanjali Yoggram. The research was carried out over 8 months. All participants received a uniform treatment protocol as prescribed by Patanjali. For the sample size determination and validation, α and 1-β was calculated and for the significance of the pre- and post-treatment QoL ratings, Shapiro wilk test and other descriptive statistics techniques were explored. Results A total of 103 patients seeking cancer special-healthcare were interviewed, out of which 39 (37.86%) remained finally based on the inclusion/exclusion criteria with age (25–65 years), types of cancers (Carcinoma and Sarcoma), chemotherapy/radiotherapy received or not, before opting Integrated-pathy. Follow-ups revealed a significant increase in the QoL (17.91%) after receiving the integrated therapy over a course of at least 1 month. Further, a significant reduction in cancer-related pain followed by an increase in QoL index was reported in the patients. Shapiro–wilk test revealed significant pairing (p < 0.001) with validation of the model using test. Conclusions To bolster evidence-based backing for Integrated-pathy, there is a need for clearly delineated clinical indicators that are measurable and trackable over time. Clinical investigators are encouraged to incorporate Integrated-pathy into their proposed interventions and conduct analogous studies to yield sustained advantages in the long run.

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Section: Introductionmentioning

confidence: 99%

Impact assessment of integrated-pathy on cancer-related fatigue in cancer patients: an observational study

Balkrishna,

Katiyar,

Ghosh

et al. 2024

J Health Popul Nutr

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“…Not much is known about the possible interactions of integrated-pathy with chemotherapy (CT), radiation therapy (RT), or biological therapies, as well as how these interactions relate to results [25]. The purpose of the current study was to nd the e cacy of integrated-pathy among cancer patients undergoing treatment at Patanjali Yoggram, Haridwar, who were also receiving the best CAM treatments and conventional CTRT.…”

Section: Introductionmentioning

confidence: 99%

Impact Assessment of Integrated-pathy on Cancer-Related Fatigue in Cancer Patients: An Observational study

Balkrishna¹,

Katiyar

Singh

et al. 2023

Preprint

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Background: Integrated-pathy aims to integrate modern medicine with traditional systems via applying the holistic approach of Ayurveda, Yoga, Yagya, Panchkarma and natural medicine. This is important for addressing the challenges surrounding the delivery of long-term palliative care for chronic ailments including cancer. The prime intent of this study was to substantiate the underlying hypothesis behind the differential and integrative approach having a positive impact on Quality of Life of cancer patients. Study Design: Observational study Methods: A standardized questionnaire was developed and used, after obtaining written informed consent from patients to assess the impact of Integrated-pathy on patients (n=103) diagnosed with cancer receiving care at Patanjali Yoggram. The research was carried out over an eight-month period (December-2021 to July-2022). For the significance of the pre- and post-treatment QoL ratings, Wilcoxon signed-rank pair test, Kolmogorov-Smirnov test and other descriptive statistics techniques were explored. Results: A total of 103 patients seeking cancer special-healthcare were interviewed, out of which 39 (37.86%) were selected based on the inclusion/exclusion criteria with age (25-65 years), period of Integrated-pathy received (≥1 months), allopathic treatment received prior to opting for Integrated-pathy. Results revealed a significant increase in the QoL (17.91%) after receiving the integrated therapy over a course of at least one month. Further, a significant reduction in cancer related pain followed by an increase in QoL index was reported in the patients. Wilcoxon rank test revealed significant pairing (p<0.0001) with validation of the model using Kolmogorov-Smirnov test. Conclusions: In order to enhance evidence-based support to the Integrated-pathy, well-defined clinical indicators that can be assessed and monitored over time are required. Clinical researchers should add Integrated-pathy into their proposed interventions and undertake similar studies to provide long-term benefits.

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“…There is increasing interest in using complementary and alternative medicines to treat various acute and chronic diseases 8,9 . These stem from their affordability, availability, and with minimum/no harmful effects.…”

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confidence: 99%

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2023

IJPSR

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Persistent Mycobacterium tuberculosis (Mtb) attributable to resistant strains has increased the burden leading to poor quality of life to the patients. Drugs of herbal origin have been identified as potential sources of new anti-tubercular agents for the treatment of this disease and emerging resistant strains of the bacterium. In this research, therefore, five herbs/plants that have been indicated in the treatment of Mycobacterium tuberculosis in the traditional/folklore medicine were evaluated for their potential use in the treatment of Mycobacterium tuberculosis infection. Garcinia kola, Picralina nitida, Mitracarpus villosus, Vernonia amygdalina and Securidaca longipedunculata were assessed for their anti-tubercular activity using standard methods. G. kola and V. amygdalina having better activity were assessed for their synergistic activity. Doses displaying in-vivo activity were established. The activity of the synergistic mix with Rifampicin was evaluated in a resistant Mtb strain. Two plants; G. kola (MIC of 125 mg/ml) and V. amygdalina (MIC of 250 mg/ml) performed better than others. The synergistic ratios of V. amygdalina, G. kola of 1:1, 2:1, 4:1 and 8:1 produced enhanced activity. An 8:1 ratio mix dose of 2500 mg/kg and above exhibited anti-tubercular activity ex-vivo. The plasma concentration of the hybrid mix interacted with Rifampicin to exhibit antitubercular activity in a resistant strain of the bacterium. V. amygdalina and G. kola in suitable ratio exerts synergistic anti-tubercular activity and interacts with Rifampicin to inhibit resistant tubercular bacilli growth.INTRODUCTION: Tuberculosis (TB) is one of the main causes of mortality and morbidity globally.

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Alternative Medicine: New Ways to Treat Diseases and Therapies

Cited by 5 publications

References 36 publications

Impact assessment of integrated-pathy on cancer-related fatigue in cancer patients: an observational study

Impact assessment of integrated-pathy on cancer-related fatigue in cancer patients: an observational study

Impact Assessment of Integrated-pathy on Cancer-Related Fatigue in Cancer Patients: An Observational study

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