The collagenous architecture is a dynamic property of the articular cartilage adapting to its respective loading situation. Crimp reflects local compressive strain. Under compressive loading larger portions of cartilage than the directly loaded areas are functionally included in the process of load transmission. During this process the tangential zone and the intermediate zone form a common functional unit providing a high degree of fiber cross-linkage as a possible mechanism to increase zonal compressive stiffness. Removal of the tangential zone seems to impair distribution of a locally applied compressive load sideways and leads to a reduced cartilage volume included in the process of load transmission. An intact tangential zone contributes to prevent peaks of surface tensile strain.