Aluminum Phosphide

Abdollahi, M.; Mehrpour, Omid

doi:10.1016/b978-0-12-386454-3.00467-x

Cited by 5 publications

(2 citation statements)

References 11 publications

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“…Consistent with our result, previous studies has reported hepatocyte vacuolation, sinusoidal congestion, fatty liver changes, centrilubolar necrosis, and destruction of nucleolus of hepatocytes in phosphine-poisoning 22,23 . Haghi et al 24 concisely discussed the mechanisms of hepatocyte phosphineinduced cytotoxicity, highlighting the production of reactive hydroxyl radicals, induction of cellular hypoxia, and free radical-mediated injury in addition to the inhibition of cytochrome C-oxidase and other essential cellular enzymes 25,26,27 . Vitamin C administration at a dose of 100 mg/kg exhibits a recovery in the ALP-induced hepatotoxicity with reparation features suggestive of regenerative changes.…”

Section: Discussionmentioning

confidence: 99%

Histopathological and Biochemical Effect of Vitamin C and D on Phosphine-Induced Hepatotoxicity in Wistar Rats

Moronkeji

Gamade

Akinbo

et al. 2023

Asian J Dental Health Sci

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Background: Aluminum phosphide is becoming a very common agent for self-poisoning. The lack of specific antidote for phosphide poisoning has aroused the current interest of research. Objectives: This study aimed to investigate the possible protective effect of Vitamin C and D in phosphine-induced hepatotoxicity in Wistar rats. Methods: In this experimental study, 20 Wistar rats were randomly divided into five groups ( n = 12). Group I was apparently normal Control Group. Groups II-V were induced with 2.5 mg/kg ALP. Groups II was without further treatment while Groups III-IV received vitamin C at 100mg/kg/bw and vitamin D at 10mg/kg/bw. Group V was co-administered with vitamin C at 100mg/kg/bw and vitamin at 10mg/kg/bw. The treatments lasted for 28 days. Results: The results showed that Vitamin C and D (P<0.05) increased antioxidant capacity. Combined active constituents of the Vitamin C and Vitamin D raised the GPX antioxidant activities when compared to the phosphine poisoned group treated individually with Vitamin C and D. The combined activities of Vitamin C and Vitamin D showed the highest antioxidant effect as compared with the control Conclusion: The combined activities of Vitamin C and D supplementation improved the antioxidant defense system and histology of the liver in phosphine poisoning. Keywords: Metal phosphide, Carotene, Liver cell damage, Poison

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Section: Discussionmentioning

confidence: 99%

Histopathological and Biochemical Effect of Vitamin C and D on Phosphine-Induced Hepatotoxicity in Wistar Rats

Moronkeji

Gamade

Akinbo

et al. 2023

Asian J Dental Health Sci

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“…Phosphine enters immediately into the bloodstream. As to its toxicokinetics, animal studies on rats suggest an LC50 of 11 ppm (15 mg/m 3 ) [ 3 ]. The gas can cause direct alveolar injury and is absorbed through the digestive tract and causes damage to the other organs by the inhibition of mitochondrial cellular respiration, cytochrome C oxidase inhibition, and subsequent production of free radicals [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Survival after Aluminum Phosphide Poisoning in Pregnancy

Lahlou

Sidayne

Benlamkaddem

et al. 2020

Case Reports in Emergency Medicine

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Changes in the population and diversity of plant parasitic nematodes and their effects on sugarcane growth at Wonji‐Shoa Sugar Estate, Ethiopia

Dengia,

Dechassa,

Wogi

et al. 2024

Agrosystems Geosci & Env

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In Wonji‐Shoa Sugar Estate (WSSE), sugarcane (Saccharum spp. hybrid) yields have declined by about 48% over the last 70 years. One of the causes for the decline is assumed to be the long‐term monoculture production system that results in the buildup of plant parasitic nematodes (PPNs). Therefore, the population and diversity of PPNs were investigated by conducting soil sampling using a biosequential method (simultaneous sampling of the soils of adjacent cultivated land [CL] and uncultivated land [UL]) and a chronosequential method (taking soil samples at different times from the same site). The samples were subjected to analysis using standard procedures to determine the change in the population, and identify the genera of PPNs. Additionally, a pot experiment that involved fumigation was conducted on top soils sampled from the CL and UL of the plantation. The results revealed that about 10 genera of PPNs (Meloidogyne, Helicotylenchus, Hoplolaimus, Rotylenchulus, Hemicycliophora, Discriconemella, Xhiphinema, Pratylenchus, Tylenchorhynchus, and Scutellonema) were detected, of which the first four were newly identified. The population density and the number of genera of PPNs found in the CL were 36‐fold and 4.5‐fold higher than those found in the UL, respectively. Furthermore, fumigation reduced the population of the PPNs by 61% and increased production of cane biomass by 63%. It is concluded that the soils of the WSSE are infested by PPNs, which consequently have detrimental effects on sugarcane growth. While amending soil fertility is crucial, reversing the decline in sugarcane yields also necessitates implementing an integrated soil management system that includes PPNs.

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Aluminum Phosphide

Cited by 5 publications

References 11 publications

Histopathological and Biochemical Effect of Vitamin C and D on Phosphine-Induced Hepatotoxicity in Wistar Rats

Histopathological and Biochemical Effect of Vitamin C and D on Phosphine-Induced Hepatotoxicity in Wistar Rats

Survival after Aluminum Phosphide Poisoning in Pregnancy

Changes in the population and diversity of plant parasitic nematodes and their effects on sugarcane growth at Wonji‐Shoa Sugar Estate, Ethiopia

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