Alveolar ridge preservation using autogenous tooth graft versus beta-tricalcium phosphate alloplast: A randomized, controlled, prospective, clinical pilot study

Abstract

Background:A randomized, prospective clinical, radiographical, and histological study was conducted to evaluate healing after alveolar ridge preservation technique using two different graft materials, namely, a novel autogenous graft material i. e., autogenous tooth graft (ATG) and beta-tricalcium phosphate (β-TCP) alloplast.Materials and Methods:Fifteen patients undergoing extraction of at least three teeth were selected. Atraumatic extractions were performed. Of the three extraction sockets, one was grafted with ATG, other with β-TCP, and the third was left ungrafted. Cone-beam computed tomography scans were taken immediately after grafting and 4 months postoperatively to check the changes in alveolar crest height and width at all the sites. Three patients in whom implant placement was done after complete healing; bone samples were harvested using a 3 mm diameter trephine during osteotomy preparation from both the ridge preserved sites and studied histologically.Results:There was a statistically significant difference when the changes in width and height of alveolar crest were compared within all the three groups (P < 0.05). Among three sites, ATG-grafted sites showed the most superior results with a minimal reduction in alveolar crest height and width. Histological analysis also showed the same trend with more new bone formation at ATG-grafted sites as compared to β-TCP-grafted sites.Conclusion:Postextraction, ridge preservation leads to more predictable maintenance of alveolar ridge height and width. ATG as compared to β-TCP provided superior results. Based on this, we conclude that ATG material can serve as a better alternative to conventional bone graft materials.

Radiographic Density Following grafting with Autogenous Tooth versus Autogenous Decalcified Dentin in Socket Preservation: a Randomized Pilot Trial.

“…The radiographic density was included as the primary outcome as it can indirectly be correlated to anatomical and histological bone quality which is advantageous for successful dental implant (Silva et al, 2012, Huang et al, 2014, Almasoud et al, 2016. The value of Hu at the ADD group in our study came in accordance with the results of the study by Jun et al 2014 The autogenous graft from teeth was compared to β-tricalcium phosphate (TCP) for socket preservation in a split-mouth randomized trial including 15 patients (Joshi et al, 2016); the bone graft derived from teeth exhibited better dimensional preservation than the alloplasts after 4 months which was statistically significant. The graft derived from teeth was also compared to deproteinized bovine bone mineral (DBBM) xenograft for their effect in halting bone resorption and for the implant rehabilitation by Pang et al (2017) and both materials were equally effective for preserving the ridge height and width as well as for implant stability afterward with no statistically significant difference.…”

Autogenous DDM versus Bio‐Oss granules in GBR for immediate implantation in periodontal postextraction sites: A prospective clinical study

“…1 Tooth-derived demineralized dentin matrix (DDM) was first introduced in 1967, and several studies have shown that DDM has a chemical composition similar to bone. [2][3][4][5] Due to chemotactic properties for osteoblasts and osteoprogenitor cells, DDM from the patient's own extracted healthy tooth can be used for promoting the bone regeneration process at reconstructive dentistry, including extraction socket preservation, ridge augmentation, sinus bone graft, and guided bone regeneration (GBR) for implant site development. [6][7][8] There continues to be controversy regarding the medical choice of retention and removal of severely loose teeth due to periodontitis.…”

“…However, they have some essential drawbacks including donor site morbidity, limited availability, and additional payment . Tooth‐derived demineralized dentin matrix (DDM) was first introduced in 1967, and several studies have shown that DDM has a chemical composition similar to bone . Due to chemotactic properties for osteoblasts and osteoprogenitor cells, DDM from the patient's own extracted healthy tooth can be used for promoting the bone regeneration process at reconstructive dentistry, including extraction socket preservation, ridge augmentation, sinus bone graft, and guided bone regeneration (GBR) for implant site development …”

Ridge augmentation using sticky bone: A combination of human tooth allograft and autologous fibrin glue

“…[11] Since then, a number of studies have shown promising results using dentin in comparison to various commercially available bone graft substitutes. [12131415] This is possibly due to the fact that bone and dentin possess similar biochemical properties. Dentin has shown to contain BMPs, insulin-like growth factor (IGF)-II, vascular endothelial growth factor, and transforming growth factor (TGF)-β. Cementum, a bone-like material surrounding tooth roots, also contains TGF-β, IGF-I, and type I and type III collagen, possibly contributing to its osteoinductive potential.…”