Alveolar soft part sarcoma of the oral and maxillofacial region: clinical analysis in a series of 18 patients

Alveolar Soft Part Sarcoma of Hypopharynx; A Case Report

“…Early diagnosis and treatment are crucial for such a rare malignancy. 28,31,32 The involvement of pharynx with ASPS is uncommon compared to other organs (tissues) at the head and neck. In the larynx, cases occur in the false vocal cord 5,8 and true vocal cord.…”

“…A prestyloid parapharyngeal space ASPS was reported with an initial complaint of painful mass and increasing dysphagia. 24 Wang et al 28 reported 18 cases of ASPS, among which one is occurring in the pharynx without a further account on presenting symptoms. This current case is unusual in that the patient did not report any symptoms related to the pharynx like cough, dysphagia, mass, or hoarseness of voice.…”

Alveolar soft part sarcoma of tongue in a 3-year-old Taiwanese

“…Thus, considering the high rates of late recurrence and metastasis, surgical resection with 1.5–2.0 cm surgical margins and long-term follow-up are adopted in our patient. On the other hand, better prognosis has been claimed for cases in children and cases in oral cavity 2 , 3 , 5 . So, potential favorable clinical outcome could be expected for the current case, which also perhaps due to the relative smaller tumor size and the early detection of oral ASPS.…”

“…Alveolar soft-part sarcoma (ASPS), which was firstly described by Christopherson et al., in 1952, 1 is a rare soft-tissue sarcoma accounting for approximately 0.5–1.0% of all soft tissue sarcomas and less than 0.1% of head and neck sarcomas 2 . ASPS occurs predominantly in adolescents and young adult from the age of 15–35, and is very rare in age less than 5 years 2 , 3 . Most ASPSs manifest as slow growing, painless intramuscular masses.…”

“…Most ASPSs manifest as slow growing, painless intramuscular masses. Head and neck region is the most common affected site for cases of infants and children with 41% at the orbit and 25% in the oral cavity 2 …”