Alvogyl or Alveogyl?

Kalsi, Hasneet K; Major, Ralph H.; Jawad, H

doi:10.1038/s41415-020-2073-x

Cited by 13 publications

(9 citation statements)

References 2 publications

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“…No papers included in this review make reference to the change in formula. In the literature, only two papers appear to highlight this change 72,73 . In a letter to the editor, Kalsi et al 72 conducted a survey of 120 UK dentists and found that 56% were unaware of the name change, with 91% unaware of the changes to the formula.…”

Section: Discussionmentioning

confidence: 99%

Aetiology, Prevention and Management of Alveolar Osteitis—A Scoping Review

Ghosh

Aggarwal

Moore

2021

J of Oral Rehabilitation

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Background Alveolar osteitis (AO) is a poorly understood, common, painful complication following exodontia. It is sometimes managed by inappropriate prescription of antibiotics which contributes to the global threat of antimicrobial resistance. Use of intra‐alveolar chlorhexidine also presents a serious risk of anaphylaxis to the patient. Objective This scoping review aims to investigate the aetiology, prevention and management of AO and highlight the extent of inappropriate prescribing and intra‐alveolar chlorhexidine use. Design A scoping review was undertaken using the PRISMA guidelines. Medline, Ovid and Pubmed were searched between 2010 and 2020, from which 63 studies were selected for review that related to the aetiology, prevention or management of AO. Data were analysed for frequency of studies reporting information on risk factors for aetiology, prevention strategies and management including inappropriate management using antibiotic prescribing and intra‐alveolar chlorhexidine. Results Impaired immune response, surgical technique and age were identified as significant factors in the development of AO, while there is conflicting evidence regarding the effects of smoking and gender. With regard to prevention, the use of prophylactic antibiotics is not supported within the literature. Saline irrigation and eugenol pastes used preventively have been shown to be cheap and effective alternatives to chlorhexidine with no adverse effects. Hyaluronic acid and low‐level laser therapies showed a significant reduction in pain and soft‐tissue inflammation in the management of AO compared to Alveogyl. Conclusions Further understanding of the pathophysiology of AO is needed, in addition to large high‐quality RCTs or long‐term observational studies into the aetiology, prevention, and management of AO to produce up‐to‐date evidence‐based clinical guidelines. Clinicians should also be mindful of their contribution to growing antimicrobial resistance and avoid inappropriate prescribing of antibiotics. Saline should replace chlorhexidine as the intra‐alveolar irrigant of choice.

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Section: Discussionmentioning

confidence: 99%

Aetiology, Prevention and Management of Alveolar Osteitis—A Scoping Review

Ghosh

Aggarwal

Moore

2021

J of Oral Rehabilitation

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“…All previous studies were done with Alvogyl, which contained butamen, iodoform, and eugenol. This medicament was replaced with Alveogyl with a different composition-eugenol and Penghawar Djambi [14]. It seems a significant proportion of dental professionals remains unaware of the change of both the name and the composition [14].…”

Section: Discussionmentioning

confidence: 99%

“…This medicament was replaced with Alveogyl with a different composition-eugenol and Penghawar Djambi [14]. It seems a significant proportion of dental professionals remains unaware of the change of both the name and the composition [14]. Another disadvantage is the non-resorbability of the material [9,29], which, in the case of improper removal, can lead to complications during the further implantation, as the material stays unresorbed in situ.…”

Section: Discussionmentioning

confidence: 99%

“…The standard treatment method used in the authors' workplace is the short-term intra-appointment placement of gauze soaked with a phenol-camphora spirituous solution in the extraction wound combined with the application of dry heat (infrared lamp) for 15 min, which brings an immediate pain relief in the majority of the patients [2]. After removal of the gauze, the extraction wound is covered with ZOE paste or filled with Alveogyl, consisting of eugenol and Penghawar Djambi [14]. The advantages are analgesia and disinfection; however, it presents several risks, such as allergic reaction, prolonged healing, and chronic inflammation.…”

Section: Introductionmentioning

confidence: 99%

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Initial Observation of Factors Interfering with the Treatment of Alveolar Osteitis Using Hyaluronic Acid with Octenidine—A Series of Case Reports

et al. 2021

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Alveolar osteitis (AO) is a common complication following the extraction of the teeth, particularly the lower third molars. It starts within a few days after the extraction and manifests mainly as pain in the extraction site. Several strategies of treatment are available in order to relieve pain and heal the extraction wound. Recently, a novel medical device combining hyaluronic acid (HA) and octenidine (OCT) was introduced for the treatment of AO. This series of case reports aims to summarize the initial clinical experiences with this new device and to highlight factors possibly interfering with this treatment. The medical documentation of five patients with similar initial situations treated for AO with HA + OCT device was analyzed in detail. Smoking and previous treatment with Alveogyl (Septodont, Saint-Maur-des-Fossés, France) were identified as factors interfering with the AO treatment with the HA + OCT device. In three patients without these risk factors, the treatment led to recovery within two or three days. The patient pretreated with Alveogyl and the smoker required six and seven applications of the HA + OCT device, respectively. According to these initial observations, it seems smoking and previous treatment with Alveogyl prolong the treatment of AO using the HA + OCT device that, in turn, shows a rapid effect if these risk factors are not present.

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“…One of the treatment options that is commonly used to treat patients suffering from the dry socket is Alvogyl. Alvogyl consists of active ingredients such as iodoform (antibacterial) and butamben (anesthetic) [ 23 ]. Alvogyl has been successfully studied in patients as it is known to provide relief from pain and discomfort in patients suffering from dry sockets [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study on Alvogyl and a Mixture of Black Seed Oil and Powder for Alveolar Osteitis: A Randomized Double-Blind Controlled Clinical Trial

Khan

Prabhu

Ahmed

et al. 2022

International Journal of Clinical Practice

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Introduction. Alveolar osteitis (AO) is the most common complication faced by exodontia patients and is usually seen 24–74 hours after tooth extraction, heralded by severe throbbing pain. Nigella sativa is commonly known as black seed known to have anti-inflammatory and antibacterial properties along with other reparative properties that enhance bone formation. This study aimed to evaluate and compare the effects of Alvogyl and a mixture of Nigella sativa powder and oil in the treatment of dry sockets. Materials and Methods. Sixty patients above the age of 18 and below 70 years, from both genders, who underwent extraction of teeth and were clinically diagnosed with a dry socket at the clinic of the College of Dentistry, Jouf University, Saudi Arabia, were included in this study. Pain scores were assessed after placement of the dressing at the following intervals: 5 minutes, 30 minutes, 60 minutes, 2nd day, 4th day, and 7th day. Patients were randomly allocated to three groups, namely, Group 1 (Alvogyl), Group 2 (mixture of Nigella sativa’s powder and oil), and Group 3 (control). Pain relief and healing of the socket were compared between the three groups. The collected data were subjected to statistical analysis through Spearman’s correlation test, independent t-test, ANOVA, and post hoc test. Results. A mixture of Nigella sativa powder and oil showed a statistically significant difference in relieving pain compared to the Alvogyl group. A mixture of Nigella sativa’s powder and oil required fewer dressings when compared to the Alvogyl group. Conclusion. A mixture of Nigella sativa powder and oil is the more efficacious dressing material for the management of dry sockets compared to Alvogyl. It provides immediate and complete pain relief and fewer numbers of repeated visits.

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Alvogyl or Alveogyl?

Cited by 13 publications

References 2 publications

Aetiology, Prevention and Management of Alveolar Osteitis—A Scoping Review

Aetiology, Prevention and Management of Alveolar Osteitis—A Scoping Review

Initial Observation of Factors Interfering with the Treatment of Alveolar Osteitis Using Hyaluronic Acid with Octenidine—A Series of Case Reports

A Comparative Study on Alvogyl and a Mixture of Black Seed Oil and Powder for Alveolar Osteitis: A Randomized Double-Blind Controlled Clinical Trial

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