Neurodegenerative Diseases 2013
DOI: 10.5772/54539
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Alzheimer’s Disease: A Clinical Perspective

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Cited by 2 publications
(2 citation statements)
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References 137 publications
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“…The reason for this decline is not well understood. However, several hypotheses, causes, and factors have been proposed to explain the deterioration in cognitive and physical function [ 136 ]. One potential cause is the poor production of mitochondrial proteins due to the impairment of cellular energy production [ 137 ].…”
Section: Mitochondrial Pathology In Nddsmentioning
confidence: 99%
“…The reason for this decline is not well understood. However, several hypotheses, causes, and factors have been proposed to explain the deterioration in cognitive and physical function [ 136 ]. One potential cause is the poor production of mitochondrial proteins due to the impairment of cellular energy production [ 137 ].…”
Section: Mitochondrial Pathology In Nddsmentioning
confidence: 99%
“…The Global Burden of Disease Study estimated that 57.4 million people globally were living with dementia in 2019 and this is predicted to reach 152.8 million people by 2050 [2]. Dementia is an umbrella syndrome characterised primarily by progressive deterioration in multiple cognitive domains, causing impairment in daily functioning across social, physical, and professional spheres [3,4]. The elderly are those primarily affected by AD [5], though this is not necessarily a direct outcome of ageing [6].…”
Section: Introductionmentioning
confidence: 99%