Amaranth as a potential dietary adjunct of lifestyle modification to improve cardiovascular risk profile

Chmelík, Zdeněk; Šnejdrlová, Michaela; Vráblík, Michal

doi:10.1016/j.nutres.2019.09.006

Cited by 22 publications

(19 citation statements)

References 61 publications

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“…Some reports have revealed that the dietary addition of amaranth can reduce the blood concentrations of cholesterol fragments (LDL and VLDL), in animals including rabbit (Caselato-Sousa et al, 2014), hamsters (Chmelik et al, 2019), and rats (Lado et al, 2015). In another study, Longato et al (2015) reported that the dietary inclusion of amaranth grain (5% and 10%) significantly decreased serum levels of triglycerides and cholesterol in broiler chickens compared to the control group.…”

Section: Discussionmentioning

confidence: 99%

Performance, Intestinal Histomorphology, and Blood Variables of Broilers Fed Amaranth Grain in Pellet Diet

Alizadeh-Ghamsari

Hosseini

Soleymani

et al. 2021

Trop. Anim. Sci. J.

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An experiment was conducted to evaluate the effects of amaranth grain in pellet diet on performance, intestinal morphology of jejunum, and selected blood variables of broilers. A total of 400 seven-day-old Ross 308 male broilers were allocated to 4 treatments with 5 replicates of 20 birds in a completely randomized design. Experimental treatments were included 4 levels of amaranth grain (0% (control), 2%, 4%, and 6%) in the isonitrogenous and isocaloric pellet diets. During the experiment, body weight (BW) and feed intake (FI) were recorded weekly and average daily gain (ADG), feed conversion ratio (FCR), as well as European broiler index (EBI), were calculated. On day 42, blood sera and jejunal tissue samples were obtained from 6 birds per replicate to evaluate morphological variables including villus height, villus width, and crypt depth, as well as selected blood variables. Although intestinal morphology and average daily feed intake (ADFI) were not influenced by experimental treatments, birds receiving 2% amaranth grain showed higher BW, ADG, and EBI compared to the other treatments (p<0.05). Chickens fed with diets including various levels of amaranth grain showed the decreased low-density lipoprotein (LDL) and cholesterol concentrations in the blood sera and reduced relative weight of abdominal fat compared to the control (p<0.05). Dietary addition of amaranth grain up to the level of 2% could improve the performance of broiler chickens, decreased blood cholesterol and LDL levels, and relative weight of abdominal fat which may have healthful effects on the birds and broiler-meat-consumers.

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Section: Discussionmentioning

confidence: 99%

Performance, Intestinal Histomorphology, and Blood Variables of Broilers Fed Amaranth Grain in Pellet Diet

Alizadeh-Ghamsari

Hosseini

Soleymani

et al. 2021

Trop. Anim. Sci. J.

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“…However, it is more effective in reducing compounds such as phytic acid. These compounds have been associated with hypocholesterolaemic, hypolipidaemic, antithrombotic, antihypertensive, antioxidant and anticancer activities (Rastogi & Shukla, 2013;Chmel ık et al, 2019;Sabbione et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the constituents potentially responsible for the hypocholesterolaemic effect have not been defined yet. This may be because of the presence of squalene, but also may be attributed to sterols, fatty acid-rich oil fractions, proteins, amino acids or fibres (Chmel ık et al, 2019). Kim et al (2006) and Sisti et al (2019) observed that the grain, oil, fibre and isolated protein of amaranth regulates glucose and serum and liver lipids, such as TC, triglyceride (TG) and very-low-density lipoprotein cholesterol (VLDL) concentrations in diabetic rats.…”

Section: Introductionmentioning

confidence: 99%

Effect of the consumption of amaranth seeds and their sprouts on alterations of lipids and glucose metabolism in mice

Corzo‐Ríos

Garduño‐Siciliano

Sánchez‐Chino

et al. 2021

Int J of Food Sci Tech

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Amaranth (Amaranthus hypochondriacus) is appreciated for its nutritional and functional quality. This study evaluated the effects of consuming amaranth seeds and their sprouts on the metabolic markers in ICR male mice. Ungerminated amaranth seeds (A) and one-day (G1) and three-day (G3) germinated amaranth sprouts were dried and milled. The mice groups (n = 10) were fed standard (N) or hypercaloric (H) diets and 1 g A, G1 or G3/kg body weight for 28 days. The total cholesterol (TC), high-and lowdensity lipoprotein (HDL and LDL), atherogenic index (AI), triglyceride (TG) and glucose levels were determined in blood samples. Germination increased the dietary fibre, phenolic and flavonoid concentration and decreased ash and squalene concentration. A, G1 or G3 consumption also decreased body weight, TC, LDL, AI and glucose levels in H group mice. Thus, amaranth seed or sprout consumption could be beneficial for people with altered lipid metabolism.

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“…Amaranth (Amaranthus L.) belongs to the pseudocereal group and is grown in Asia and the Americas [12,13]. Among the many species of amaranth, the most popular are Amaranthus caudatus L., Amaranthus cruentus L. and Amaranthus hypochondriacus L. [14].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Effect of Amaranth Oil vs. Rapeseed Oil on Selected Atherosclerosis Markers in Overweight and Obese Subjects: A Randomized Double-Blind Cross-Over Trial

Jamka

Morawska

Krzyżanowska-Jankowska

et al. 2021

IJERPH

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It is well known that rapeseed oil improves lipid profile and has antiatherosclerotic properties. Recently, amaranth oil has also become popular due to its potential health benefits. However, the effect of this oil on atherosclerosis markers in humans is not clear. Therefore, this study aimed to compare the effect of amaranth and rapeseed oils on selected atherosclerosis-related parameters in overweight and obese subjects. In this randomized cross-over study, 44 subjects were instructed to consume 20 mL of amaranth oil and rapeseed oil during two consecutive three-week intervention periods separated by a washout period of the same duration as the intervention. The outcome variables included changes in tumor necrosis factor-alpha, adiponectin, oxidized low-density lipoprotein, apolipoproteins (Apo) A1, B and E as well as glucose and insulin homeostasis markers. Compared to rapeseed oil, amaranth oil had a slight positive effect on adiponectin levels (mean (95% confidence interval): 0.55 (0.22–0.89) vs. -0.29 (−0.75–0.16), p = 0.0002) but negatively affected ApoB concentrations (0.05 (−0.01–0.11) vs. 0.03 (−0.07–0.00), p = 0.0004) and ApoB/A1 ratio (0.01 (−0.03–0.05) vs. −0.02 (−0.04–0.00), p = 0.0113). No differences between the other analyzed parameters were observed. In conclusion, amaranth oil does not have a greater beneficial effect on atherosclerosis markers than rapeseed oil. However, further studies with a longer intervention period are needed. The study was retrospectively registered with the German Clinical Trials Register within the number: DRKS00014046, date of registration: 3 May 2018.

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Amaranth as a potential dietary adjunct of lifestyle modification to improve cardiovascular risk profile

Cited by 22 publications

References 61 publications

Performance, Intestinal Histomorphology, and Blood Variables of Broilers Fed Amaranth Grain in Pellet Diet

Performance, Intestinal Histomorphology, and Blood Variables of Broilers Fed Amaranth Grain in Pellet Diet

Effect of the consumption of amaranth seeds and their sprouts on alterations of lipids and glucose metabolism in mice

Comparison of the Effect of Amaranth Oil vs. Rapeseed Oil on Selected Atherosclerosis Markers in Overweight and Obese Subjects: A Randomized Double-Blind Cross-Over Trial

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