Ambient fine particulate pollution and daily morbidity of stroke in Chengdu, China

Abstract

IntroductionAssociation has been reported between ambient fine particulate matter (PM) and adverse outcomes of cerebrovascular events. However, it remains unclear that whether short-term exposure to PM relates to stroke and the lag of health effects. This triggers us to examine the relationship between PM and population stroke morbidity in Chengdu.MethodsThe daily average concentration of atmospheric pollutants and meteorological factors and daily morbidity of stroke in Chengdu (2013–2015) were collected. Based on time series analysis-generalized additive models (GAM), single-pollutant, two-pollutant and multi-pollutant model were established. The effects of atmospheric PM2.5 (defined as PM less than 2.5μm in aerodynamic diameter), PMc(defined as PM less than 10μm and more than 2.5μm in aerodynamic diameter) and PM10 (defined as PM less than 10μm in aerodynamic diameter) concentration on the daily mortality of stroke were analyzed, respectively.ResultsThe three-year mean concentrations of PM2.5, PMc and PM10 for air pollutants were 75.9, 43.9 and 119.7 μg/m3, respectively. PM2.5 on the current day (lag0) and with a moving average of 0–1 days were significantly associated with the increasing risk of stroke morbidity, and PM2.5 with a lag of 0–1 days had greater association, whereas for PMc and PM10 there were no significant association observed. In our study, every 10μg/m3 increase of PM2.5 was associated with 0.69% percent change in stroke morbidity (95%CI: 0.01~1.38). For females, every 10μg/m3 increase of PM2.5 contributes to 0.80% percent change of onset. And for the group of age less than 65, we observed 0.78% higher risk every 10μg/m3 increase of PM2.5.ConclusionsThese findings suggest that short-term exposure to PM2.5 within 1 day is associated with the onset of stroke, and the younger people (age<65) and females are more sensitive than older people and males.

Acute Effect of Particulate Matter Pollution on Hospital Admissions for Stroke among Patients with type 2 Diabetes in Beijing, China, from 2014 to 2018

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“…The effect size of PM 2.5 was much higher than that of PM 10 , which is generally consistent with existing studies (Huang et al, 2016;Zeng et al, 2018). Several mechanisms were proposed to explain the difference.…”

The Relationship between Daily Concentration of Fine Particulate Matter in Ambient Air and Exacerbation of Respiratory Diseases in Silesian Agglomeration, Poland

“…Another important issue in environmental epidemiology studies is the method of exposure estimation [15]. Usually, researchers assess the short-term health effects relating to increases in air pollutant concentration by the moving average concentration of pollution [16,17] or temporal lags (1–30 days) as a measure of exposure [18,19,20]. Commonly used models assess the risk ratio of health effects in response to an increase in pollutant concentration by a unit of a single IQR value.…”

Short-term associations between ambient air pollution and stroke hospitalisations: time-series study in Shenzhen, China

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