Ameliorative effects of Mentha aquatica on diabetic and nephroprotective potential activities in STZ-induced renal injury

Konda, Prabhakar Yellanur; Egi, Janardhan Yadav; Dasari, Sreenivasulu; Katepogu, Raju; Jaiswal, Krishna Kumar; Prabhusaran, N

doi:10.1007/s00580-019-03042-6

Cited by 15 publications

(4 citation statements)

References 19 publications

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“…In addition, both plants acted positively on histopathological tissues of the liver and pancreas. Furthermore, in a study by Yellanur et al (2020) a dose of 100 mg/kg bw/day of Mentha aquatica aqueous extract for 90 days significantly reduced levels of fasting glycaemia, HbA1c (glycated hemoglobin test), TC, TG, plasma urea, creatinine, urinary albumin, and renal lipid peroxidation, and increased BW, insulin, HDL cholesterol, plasma albumin, urinary urea, urinary creatinine, and antioxidant enzyme activities (CAT, SOD, GPx, and GST) [ 492 ]. The authors demonstrated that the aqueous extract of M. aquatica leaves has antidiabetic activity by stimulating insulin secretion and potential nephroprotective activity by reducing lipid peroxidation and enhancing the scavenging capacity of the antioxidant defence system in the body [ 492 ].…”

Section: Resultsmentioning

confidence: 99%

Overview of Ethnobotanical–Pharmacological Studies Carried Out on Medicinal Plants from the Serra da Estrela Natural Park: Focus on Their Antidiabetic Potential

Lahlou,

Carvalho,

Pereira

et al. 2024

Pharmaceutics

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The Serra da Estrela Natural Park (NPSE) in Portugal stands out as a well-preserved region abundant in medicinal plants, particularly known for their pharmaceutical applications in diabetes prevention and treatment. This comprehensive review explores these plants’ botanical diversity, traditional uses, pharmacological applications, and chemical composition. The NPSE boast a rich diversity with 138 medicinal plants across 55 families identified as traditionally and pharmacologically used against diabetes globally. Notably, the Asteraceae and Lamiaceae families are prevalent in antidiabetic applications. In vitro studies have revealed their significant inhibition of carbohydrate-metabolizing enzymes, and certain plant co-products regulate genes involved in carbohydrate metabolism and insulin secretion. In vivo trials have demonstrated antidiabetic effects, including glycaemia regulation, insulin secretion, antioxidant activity, and lipid profile modulation. Medicinal plants in NPSE exhibit various activities beyond antidiabetic, such as antioxidant, anti-inflammatory, antibacterial, anti-cancer, and more. Chemical analyses have identified over fifty compounds like phenolic acids, flavonoids, terpenoids, and polysaccharides responsible for their efficacy against diabetes. These findings underscore the potential of NPSE medicinal plants as antidiabetic candidates, urging further research to develop effective plant-based antidiabetic drugs, beverages, and supplements.

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Section: Resultsmentioning

confidence: 99%

Overview of Ethnobotanical–Pharmacological Studies Carried Out on Medicinal Plants from the Serra da Estrela Natural Park: Focus on Their Antidiabetic Potential

Lahlou,

Carvalho,

Pereira

et al. 2024

Pharmaceutics

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show abstract

“…To stabilize and improve the bioavailability of the drug molecules, NE as a delivery system can be a suitable approach for solving these issues (Akhtar et al, 2016;Nanjwade et al, 2013). Several in vitro and in vivo studies have reported the antidiabetic activity of biologically active herbal formulations from Mentha aquatica, Syzygium paniculatum Gaertn, pectinase -treated probiotic banana juice, Persea americana, Mangifera indica, to name a few for the treatment of hyperglycemia conditions (Konda et al, 2020(Konda et al, , 2021Ojo et al, 2022;Sudha Madhuri & Mohanvelu, 2017;Yellanur et al, 2020). Therefore, NE as a delivery vehicle can be applied to these novel phytocompounds to enhance their effectiveness and biopharmaceutical properties.…”

Section: Eos Ofmentioning

confidence: 99%

Plant‐based essential oil encapsulated in nanoemulsions and their enhanced therapeutic applications: An overview

Jamir,

Bhushan,

Sanjukta

et al. 2023

Biotech & Bioengineering

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In recent years, studies on the formulation of nanoemulsions have been the focus of attention due to their potential applicability in food, pharmaceuticals, cosmetics, and agricultural industries. Nanoemulsions can be formulated using ingredients approved by the Food and Drug Administration (FDA), which assures their safety profiles to a great extent. Bioactive compounds such as essential oils although have strong biological properties and antimicrobial compounds, their usage is restricted due to their high volatility, instability, and hydrophobic nature. Therefore, nanoemulsion as carrier vehicle can be used to encapsulate essential oils to obtain stable and enhanced physicochemical characteristics of the essential oils. This review details the structure, formulation, and characterization techniques used for nanoemulsions, with a focus on the essential oil‐based nanoemulsions which have the potential to be used as antimicrobial and anticancer therapeutics.

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“…often utilized as a smell component in toothpaste, cleansers, cosmetics, and modern scents (Alvi et al, 2001) Table 3. [71][72][73][74]…”

Section: Use In Industriesmentioning

confidence: 99%

Ethanopharmacological Activities of Mentha arvensis: An Updated Review

Mazumder,

Das

2023

IJDDT

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Economical natural menthol is derived from Mentha arvensis Linn (menthol mint) oil. It is an aromatic perennial herb. The leading Mentha producing state in area and production is Uttar Pradesh and India is the leading exporter contributing about 80% of essential oil, menthol crystal and allied products. It is a native herb from the Labiatae family and is most frequently referred to as “pudina”. It has historically been used to treat ischemic heart disease and hypertension. Terpenoids, alcohols and phenolics are just a few of the bioactive substances that have been identified from this plant. These bioactive compounds’ pharmacological activities include antibacterial, neuroprotective, antioxidant, antiulcer, immunomodulatory, antimutagenic, and anti-tumor properties. Studies on Ayurvedic, unani, and other traditional medical systems have also revealed this plant’s pharmacological capabilities. The current article provides a summary of the plant’s general description, phytochemical ingredients, historical context, and pharmacological qualities

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Ameliorative effects of Mentha aquatica on diabetic and nephroprotective potential activities in STZ-induced renal injury

Cited by 15 publications

References 19 publications

Overview of Ethnobotanical–Pharmacological Studies Carried Out on Medicinal Plants from the Serra da Estrela Natural Park: Focus on Their Antidiabetic Potential

Overview of Ethnobotanical–Pharmacological Studies Carried Out on Medicinal Plants from the Serra da Estrela Natural Park: Focus on Their Antidiabetic Potential

Plant‐based essential oil encapsulated in nanoemulsions and their enhanced therapeutic applications: An overview

Ethanopharmacological Activities of Mentha arvensis: An Updated Review

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