2023
DOI: 10.1097/hc9.0000000000000108
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American College of Sports Medicine (ACSM) International Multidisciplinary Roundtable report on physical activity and nonalcoholic fatty liver disease

Abstract: Background and Aims: We present findings from the inaugural American College of Sports Medicine (ACSM) International Multidisciplinary Roundtable, which was convened to evaluate the evidence for physical activity as a means of preventing or modifying the course of NAFLD. Approach and Results: A scoping review was conducted to map the scientific literature and identify key concepts, research gaps, and evidence available to inform clinical practice, policymaking, and research… Show more

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Cited by 38 publications
(26 citation statements)
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“…Nonalcoholic fatty liver disease (NAFLD) continues to be a leading cause of chronic liver disease worldwide of great public health interest 1 . Because physical inactivity and sedentary behaviour contribute heavily to disease pathogenesis, lifestyle modification with increased physical activity is a key intervention against NAFLD 2,3 . However, physical inactivity and other environmental factors do not act in isolation; rather, there is a complex interaction between environmental factors and a genetic predisposition that we are beginning to understand 4 .…”
Section: Figurementioning
confidence: 99%
See 3 more Smart Citations
“…Nonalcoholic fatty liver disease (NAFLD) continues to be a leading cause of chronic liver disease worldwide of great public health interest 1 . Because physical inactivity and sedentary behaviour contribute heavily to disease pathogenesis, lifestyle modification with increased physical activity is a key intervention against NAFLD 2,3 . However, physical inactivity and other environmental factors do not act in isolation; rather, there is a complex interaction between environmental factors and a genetic predisposition that we are beginning to understand 4 .…”
Section: Figurementioning
confidence: 99%
“…1 Because physical inactivity and sedentary behaviour contribute heavily to disease pathogenesis, lifestyle modification with increased physical activity is a key intervention against NAFLD. 2,3 However, physical inactivity and other environmental factors do not act in isolation; rather, there is a complex interaction between environmental factors and a genetic predisposition that we are beginning to understand. 4 Genome-wide association studies have allowed for the creation of polygenic risk scores for hepatic fat content.…”
Section: Sweating It Out: How Physical Activity Can Combat High Genet...mentioning
confidence: 99%
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“…Despite the well‐known high economic impact of MASLD, there remains no regulatory agency‐approved cure or effective drug treatment, although several promising therapeutics are on the horizon 10 . Accordingly, lifestyle modifications such as dietary changes and increasing physical activity are the mainstay of management and will likely remain so even when approved drug therapy is widely available 11–15 . Physical activity, particularly exercise training, has been shown to reduce liver fat measured by magnetic resonance imaging (MRI) 16 .…”
Section: Introductionmentioning
confidence: 99%