Amino Acid Metabolism in the Sheep Foetus

Alexander, D. Pauline; Britton, H.G.; Nixon, D. A.; Cox, Bettye

doi:10.1159/000240235

Cited by 6 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The resulting ratio between fetal and adult plasma amino acids is 1.6, a value which corresponds well with ratios found comparing human [14], monkey [12], or sheep cord blood [1] with the respective maternal blood. It should be noted that we have analyzed arterial blood from adult nonpregnant rabbits while other authors have used venous blood from mothers.…”

Section: Resultssupporting

confidence: 81%

Perinatal Changes of Plasma Free Amino Acids in Normal and Hypoxic Rabbits

Stave¹,

Armstrong²

1972

Neonatology

View full text Add to dashboard Cite

Section: Resultssupporting

confidence: 81%

Perinatal Changes of Plasma Free Amino Acids in Normal and Hypoxic Rabbits

Stave¹,

Armstrong²

1972

Neonatology

View full text Add to dashboard Cite

“…The use of ion-exchange chromatography has allowed other workers to make much more comprehensive studies of fetal fluids in sheep and women. For example, Alexander et al (1970) and Hopkins et al (1971) reported that fetal sheep had plasma FAA levels that were more than twice the maternal FAA levels and that the fetal levels did not vary significantly even though the maternal FAA levels altered over a wide range by perfusion or starvation. In studies with human fetuses, Scott et al (1972) examined the changes in indivi-dual FAA concentrations in amniotic fluid and proposed that the FAA con¬ centrations could be used as an indicator of fetal age.…”

Section: Introductionmentioning

confidence: 99%

Developmental Changes of Free Amino Acids in Bovine Fetal Fluids With Gestational Age and the Interrelationships Between the Amino Acid Concentrations in the Fluid Compartments

Baetz¹,

Hubbert²,

Graham³

1975

Reproduction

View full text Add to dashboard Cite

Summary. Thirty ninhydrin-positive compounds were determined in the sera, amniotic fluid, stomach content and allantoic fluid from 29 bovine fetuses of various gestational ages. Fetal serum was found to contain about 3-fold higher concentrations of free amino acids (FAA) than maternal serum, and allantoic fluid contained about 3-fold higher concentration of FAA than fetal serum. Decreasing concentrations of FAA were found in serum as a function of the crown-rump length for the amino acids taurine, aspartic acid, threonine, serine, ornithine and lysine. Decreasing concentrations of FAA in allantoic fluid were found for threonine, alanine and ornithine, whereas increasing concentrations were found for phosphoserine and methionine as a function of the crown-rump length. Correlations were found between the concentrations of most amino acids in amniotic fluid and stomach content, but fewer correlations were found between the other fluid compartments. The transport of amino acids between compartments is discussed.

show abstract

“…Thus in the menstrual cyete or pregnancy changes in amino acid levels may be a secondary passive response to changes in levels of progesterones or oestrogens, rather than a primary response indicating greatly increased rates of extraction or production, as demonstrated by the similar response of normal men to progesterone and oestrogen administration. Although the changes in metabolism which occur during pregnancy, with the high extraction rate of amino acids against a concentration gradient across the placental barrier (Young andPrenton 1967, Alexander, Britton, Nixon andCox 1970) would also tend to lead to decreased levels of plasma amino acids in the undernourished pregnan t woman. EndoerinoI.Metab.…”

mentioning

confidence: 99%

Changes in Plasma Amino Acid Levels during the Human Menstrual Cycle and in Early Pregnancy. A Preliminary Report

Cox¹,

Calame²

1978

Horm Metab Res

View full text Add to dashboard Cite

Fasting plasma amino acids have been measured in two normal females. In one subject changes in the levels of the amino acids have been followed weekly during four normal menstrual cycles. In the second subject changes in amino acid levels have been followed through a normal cycle, conception and early pregnancy. During a normal menstrual cycle it has been found that not all amino acids behave in a similar fashion. At least three distinct patterns of behaviour in respect of changes of concentration have been identified. In pregnancy it has been found that the depression in amino acid levels, reported by other workers in later pregnancy, in fact occur immediately following conception. The changes in levels of plasma amino acids which occur during the menstrual cycle and in pregnancy appear to be inversely related to the reported changes in progesterone levels which occur during these physiological events.

show abstract

Amino Acid Metabolism in the Sheep Foetus

Cited by 6 publications

References 0 publications

Perinatal Changes of Plasma Free Amino Acids in Normal and Hypoxic Rabbits

Perinatal Changes of Plasma Free Amino Acids in Normal and Hypoxic Rabbits

Developmental Changes of Free Amino Acids in Bovine Fetal Fluids With Gestational Age and the Interrelationships Between the Amino Acid Concentrations in the Fluid Compartments

Changes in Plasma Amino Acid Levels during the Human Menstrual Cycle and in Early Pregnancy. A Preliminary Report

Contact Info

Product

Resources

About