Amino−functionalized Fe(III)−Based MOF for the high−efficiency extraction and ultrasensitive colorimetric detection of tetracycline

Li, Zongda; Meng, Fanxing; Li, Ruizhi; Yan, F.; Cui, Yincang; Qin, Yueping; Zhang, Minwei

doi:10.1016/j.bios.2023.115294

Cited by 31 publications

(9 citation statements)

References 26 publications

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“…To the best of our knowledge, the linear range and LOD are comparable and even superior to those of previously reported fluorescent TC sensors (Table S2). − …”

Section: Resultsmentioning

confidence: 99%

Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline

Zhu,

Chen,

Zeng

et al. 2023

ACS Sens.

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Fluorescent point-of-care (POC) sensors have found great utility in fields like clinical diagnosis, food testing, and environmental monitoring. Herein, we developed a highly stable POC sensor that enabled the visual detection of tetracycline (TC) in a distinct fluorescent-traffic-light manner. In the sensor, a composite material of copper nanoclusters and metal–organic framework (CuNCs@MOF-5) prepared with a facile one-pot synthetic strategy was employed as the core element for target recognition and signal transduction. As evidenced by experiments, the as-prepared CuNCs@MOF-5 exhibited significantly improved fluorescence properties in terms of emission enhancement (about 28-fold) and stability improvement (over 110 days) compared to the CuNCs without confining and protection by MOF-5. More importantly, it was found that TC could uniquely interact with Zn(II) to trigger the disassembly of CuNCs@MOF-5, resulting in green fluorescence emission from the TC–Zn(II) complex and red fluorescence weakening of CuNCs. On the basis of this finding, a simple and stable sensor was proposed for POC detection of TC, which demonstrated high sensitivity, selectivity, and reproducibility. In addition to homogeneous visual detection in a 96-well plate, a CuNCs@MOF-5-contained agarose gel array was easily fabricated to achieve direct detection of TC in milk without any pretreatment, thanks to the size-sieving effect of the gel. Moreover, a test paper array was also put forward for low-cost TC detection, which indicates the extensibility and practicability of this sensing strategy.

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“…To the best of our knowledge, the linear range and LOD are comparable and even superior to those of previously reported fluorescent TC sensors (Table S2). − …”

Section: Resultsmentioning

confidence: 99%

Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline

Zhu,

Chen,

Zeng

et al. 2023

ACS Sens.

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“…7−9 Interestingly, some MOFs possess intrinsic enzyme-mimicking activity since their metal sites can simulate the active centers of natural enzymes. 10,11 Among them, Fe-based MOFs (e.g., Fe-MIL-88) have both peroxidaselike activity for colorimetric detection 12,13 and Fenton-like catalytic degradation properties for the removal of organic pollutants. 14,15 In addition, to further improve the catalytic activity for monometallic Fe-based MOFs, some bimetallic Febased MOF mimics with good electronic structures and chemical properties have been reported because their bimetallic centers can produce synergistic effects, 16 such as Fe−Cu-MOFs, 17 Fe−Ni-MOFs, 18 and Fe−Mn-MOFs.…”

Section: Introductionmentioning

confidence: 99%

Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁

Lin,

Li,

et al. 2024

ACS Appl. Mater. Interfaces

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Building multifunctional platforms for integrating the detection and control of hazards has great significance in food safety and environment protection. Herein, bimetallic Fe−Cobased metal−organic frameworks (Fe−Co-MOFs) peroxidase mimics are prepared and applied to develop a bifunctional platform for the synergetic sensitive detection and controllable degradation of aflatoxin B 1 (AFB 1 ). On the one hand, Fe−Co-MOFs with excellent peroxidase-like activity are combined with target-induced catalyzed hairpin assembly (CHA) to construct a colorimetric aptasensor for the detection of AFB 1 . Specifically, the binding of aptamer with AFB 1 releases the prelocked Trigger to initiate the CHA cycle between hairpin H2-modified Fe−Co-MOFs and hairpin H1-tethered magnetic nanoparticles to form complexes. After magnetic separation, the colorimetric signal of the supernatant in the presence of TMB and H 2 O 2 is inversely proportional to the target contents. Under optimal conditions, this biosensor enables the analysis of AFB 1 with a limit of detection of 6.44 pg/mL, and high selectivity and satisfactory recovery in real samples are obtained. On the other hand, Fe−Co-MOFs with remarkable Fenton-like catalytic degradation performance for organic contaminants are further used for the detoxification of AFB 1 after colorimetric detection. The AFB 1 is almost completely removed within 120 min. Overall, the introduction of CHA improves the sensing sensitivity; efficient postcolorimetric-detection degradation of AFB 1 reduces the secondary contamination and risk to the experimental environment and operators. This strategy is expected to provide ideas for designing other multifunctional platforms to integrate the detection and degradation of various hazards.

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“…Metal–organic frameworks − (MOFs) are porous crystalline materials that have been utilized as separators in many fields, such as chromatography, − breakthrough, − membrane separation, − and extraction . Regulating the mass transfer of analytes in MOFs is theoretically feasible because of the designable and adjustable MOF structures .…”

Section: Introductionmentioning

confidence: 99%

“…Metal−organic frameworks 9−13 (MOFs) are porous crystalline materials that have been utilized as separators in many fields, such as chromatography, 14−19 breakthrough, 20−22 membrane separation, 23−26 and extraction. 27 Regulating the mass transfer of analytes in MOFs is theoretically feasible because of the designable and adjustable MOF structures. 28 In previous studies, reducing the mass transfer resistance of analytes to enhance diffusion has already been proven as an effective approach for achieving high-efficiency separators.…”

Section: ■ Introductionmentioning

confidence: 99%

Increasing Mass Transfer Resistance of MOFs as a Reverse Tuning Strategy to Achieve High-Resolution Gas Chromatographic Separation

Yang,

Liu,

Tang

et al. 2023

Anal. Chem.

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Amino−functionalized Fe(III)−Based MOF for the high−efficiency extraction and ultrasensitive colorimetric detection of tetracycline

Cited by 31 publications

References 26 publications

Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline

Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline

Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁

Increasing Mass Transfer Resistance of MOFs as a Reverse Tuning Strategy to Achieve High-Resolution Gas Chromatographic Separation

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Amino−functionalized Fe(III)−Based MOF for the high−efficiency extraction and ultrasensitive colorimetric detection of tetracycline

Cited by 31 publications

References 26 publications

Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline

Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline

Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B1

Increasing Mass Transfer Resistance of MOFs as a Reverse Tuning Strategy to Achieve High-Resolution Gas Chromatographic Separation

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Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁