Ammonia Modified MXene/Aniline Copolymers Electrochemical Sensors for Ultrasensitive Sensing Glutathione

Abstract

Herein, unique ammonia modified MXene/aniline copolymers (PTA) are prepared by facile and green electropolymerization with the rose-like ammonia modified MXene (N-Ti 3 C 2 T x ) and aniline to modify electrochemical sensor to detect GSH with high performance. Scanning electron microscopy (SEM), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV) characterizations show that the PTA copolymer exhibits a net-like structure and excellent electrochemical performance. It displays that the PTA can be regarded as an outstanding electrode nanomaterial for high-performance sensors. Moreover, the PTA/GCE biosensor is fabricated through one-step electropolymerization method for detecting glutathione. Under the optimum conditions, the limit of detection of the biosensor is calculated to be 5.21 × 10 À 14 mol L À 1 with a high sensitivity of 32.9 μA nmol À 1 L cm À 2 . At the same time, the biosensor displays excellent selectivity and stability. Furthermore, the fabricated PTA/GCE biosensor is applied to detect glutathione of plasma samples with good recoveries, indicating that the sensor has broad application prospects in the field of biological and medical analysis.

MXene Supported Surface Plasmon Polaritons for Optical Microfiber Ammonia Sensing

“…Additionally, a new peak at 401.6 eV (Figure 2c), associated with the N element, is discernible in the XPS survey spectra. 53 These results directly indicate the adsorption of the NH 3 molecules on the MXene flakes via the binding of H atoms with −O terminals, further leading to the electrons transfer. Figure 2d displays a typical optical photo of a pristine (bare) microfiber with a diameter of 7.8 μm.…”

“…Consequently, this interaction results in a downward shift in the binding energy. Additionally, a new peak at 401.6 eV (Figure c), associated with the N element, is discernible in the XPS survey spectra . These results directly indicate the adsorption of the NH 3 molecules on the MXene flakes via the binding of H atoms with −O terminals, further leading to the electrons transfer.…”

Prudently designed Se@fMWCNT as a peroxidase mimicking nanozyme for distinctive electrochemical detection of H2O2 and glutathione

“…The obtained analytical parameters are comparable or better than for the recently reported sensors for GSH detection. 27,28,57,[59][60][61] Furthermore, fMWCNT/GCE was employed for its ability to detect H 2 O 2 and GSH as shown in Fig. S4(a and b) (ESI †).…”

“…[23][24][25][26] The optimum level of GSH in blood should lie in the range 1-10 Â 10 À3 mol L À1 for a healthy individual. 27 Abnormal concentrations of GSH are known to cause several diseases, including cancers, diabetes, Parkinson's disease and Alzheimer's disease. Therefore, the detection of GSH is pivotal in order to ameliorate living standards.…”