Amnion Membrane Graft Dressing in Superficial Partial Thickness Burn in Pediatric Patients

Abstract

Objective: The aim of this study was to find out the effectiveness of amniotic membrane graft dressing in the treatment of superficial partial thickness burn in children. Methods: The retrospective study was conducted on the patients admitted with superficial partial thickness burn in the burn unit of Dhaka Shishu Hospital age 0-12 years, during the period from January 1999 to December 2011. All of them treated with amnion membrane graft dressing. Results: Total 370 patients were included in this study. Mean age was 2.76 years. Amnion dressing suppresses bacteria in the wound as well as reduced infection. Amnions have good adherent characteristics, which reduced infection as well as reduction of oozing of plasma from the wound, that become dry early. It has a role on burnt pain reduction, Frequency of dressing change, rate of healing, cost, duration hospital stay. Conclusion: Our experience showed that amniotic membrane is one of the effective biological skin substitutes used in burn wounds, with efficacy of low bacterial counts, has advantageous of reducing protein loss, electrolytes & fluids. Decreasing the risk of infection minimizing pain, accelerate of wound healing and good handling properties. It is ready available does not present immunological problem and allergies response. It is cost effective and very helpful for developing countries.

Short-term outcomes following amniotic membrane and conventional dressing in skin graft donor site; a randomized clinical trial

“…In the study by Branski et al (21), the use of amniotic membrane was not associated with an increased risk of local infection. Several experimental animal studies have confirmed the antimicrobial properties of amniotic membrane in reducing wound infection (21)(22)(23)(24)(25). In another study by Bujang et al (24), silver sulfadiazine dressing was used as well but the rate of wound infection was lower in the amniotic dressing group again.…”

Processing and Use of Radiation Sterilized Human Amniotic Membrane Allografts as Biological Dressings of Wounds in Children: A Review

“…Shahid et al 53 reported the use of radiation sterilized amniotic membrane as local burn wound coverage and demonstrate that amniotic membrane is a suitable and effective biological dressing in reducing patient's morbidity when compared with non-biological medicated tulle (sofratulle). Ullah et al 54 reported the use of radiation sterilized amniotic membranes in the treatment ofa total of 370 patients (mean age 2.76 years) with superficial partial thickness burn. The authors 54 mention that amnion dressing suppresses bacteria in the wound as well as reduces infection.…”

“…Ullah et al 54 reported the use of radiation sterilized amniotic membranes in the treatment ofa total of 370 patients (mean age 2.76 years) with superficial partial thickness burn. The authors 54 mention that amnion dressing suppresses bacteria in the wound as well as reduces infection. Amnions have good adherent characteristics, which reduces infection as well as reduction of oozing of plasma from the wound.…”

“…Amnions have good adherent characteristics, which reduces infection as well as reduction of oozing of plasma from the wound. 54 Burn injuries are one of the most devastating physical and psychological injuries that a person can suffer. 55 From 1981 to 1990 it was the second most common surgical problem in paediatric age group in the department of pediatric surgery, Dhaka Shishu Hospital.…”

“…55 From 1981 to 1990 it was the second most common surgical problem in paediatric age group in the department of pediatric surgery, Dhaka Shishu Hospital. 56 Ullah et al 54 reported the use of radiation sterilized amniotic membranes in the treatment of a total of 370 patients with partial thickness burn. The authors mention that amnion dressing suppresses bacteria in the wound as well as reduces infection.…”