Amoebiasis: diagnosis by aspiration and exfoliative cytology

Bhambhani, Suresh; Kashyap, Veena

doi:10.1046/j.1365-2303.2001.00333.x

Cited by 20 publications

(11 citation statements)

References 5 publications

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“…The clinical and radiological presentation of ALA is nonspecific, occurring in various infections (parasitic, tuberculous and pyogenic) and in malignancy [14]. On imaging modalities, ALAs are round to ovoid with irregular wall, and attempts to differentiate this lesion from a pyogenic abscess based solely on radiological findings is a difficult task because the findings are nonspecific.…”

Section: Discussionmentioning

confidence: 99%

“…A characteristic feature of E. histolytica is phagocytosis of erythrocytes [15]. In ambiguous cases, special stains such as periodic acid-Schiff and iron may help to spot the amoebae in an inflammatory background [14]. Aspiration of the abscess wall increases the possibility of parasite detection [14].…”

Section: Discussionmentioning

confidence: 99%

“…In ambiguous cases, special stains such as periodic acid-Schiff and iron may help to spot the amoebae in an inflammatory background [14]. Aspiration of the abscess wall increases the possibility of parasite detection [14]. Because of the immunologic response against E. histolytica , serology has become a valuable adjunct for ALA diagnosis.…”

Section: Discussionmentioning

confidence: 99%

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Amebic Liver Abscess: Fine Needle Aspiration Diagnosis

Mokhtari¹,

Kumar²

2014

Acta Cytologica

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Objective: To describe the findings in fine needle aspiration (FNA) of an amebic liver abscess (ALA). Study Design: Seven patients (6 men and 1 woman between 52 and 60 years of age) treated for amebic dysentery with multiple liver lesions were selected for ultrasound (US)-guided FNA. The clinical differential diagnosis was malignancy. Abdominal US of the patients revealed multiple, variably sized, well-defined, hypoechoic, cystic liver lesions. FNA of these lesions was performed. Results: Smears of the aspirated material showed necrotic material with mixed inflammatory cells and Entamoeba histolytica trophozoites consisting of round blue bodies with well-defined borders containing a single, eccentrically located nucleus with central karyosome and engulfed red blood cells in the cytoplasm. There were also Charcot-Leyden crystals. ALA was diagnosed. Conclusion: FNA can yield the correct diagnosis of ALA and allows early initiation of treatment. ALA should be considered in the differential diagnosis of space-occupying lesions of the liver.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Amebic Liver Abscess: Fine Needle Aspiration Diagnosis

Mokhtari¹,

Kumar²

2014

Acta Cytologica

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“…Common etiological sites include biliary tract, appendiceal abscess, crohn's disease and colonic diveirticulitis. 19 E.coli is the commonest pathogen but both aerobic and anaerobic organisms are frequently found. Ultrasound will usually show a spherical, oval or slightly irregular echopoor lesion with distal enhancement.…”

Section: Liver Abscessmentioning

confidence: 99%

Sonographic Evaluation of Focal and Diffuse Hepatic Lesions

P¹,

Shukla²,

Krishnappa³

2014

jemds

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AIM:To study ultrasonography as prime imaging modality for evaluation of focal and diffuse liver lesions and its confirmation by fine needle aspiration. METHODOLOGY: Patients presenting with liver diseases were included in the study. Ultrasonography was done as initial imaging method, and then guided Fine Needle Aspiration was done to correlate our findings. RESULTS: Ultrasonography was highly sensitive and specific in diagnosing liver abscess, malignant liver tissue & metastasis. For non-malignant liver lesions like haemangioma, cystic and hydatid lesions, fatty liver and cirrhosis showed sensitivity up to 80%, and specificity up to 90%. CONCLUSION: Above data suggests that ultrasonography has high sensitivity and specificity for overall diagnosis and it helps in guiding Fine Needle Aspiration for confirmation of diagnosis. KEYWORDS:Ultrasonography, Fine Needle Aspiration, Focal and diffuse hepatic lesions. INTRODUCTION:Liver diseases like infections, metabolic and neoplastic are of the most significant causes of morbidity and mortality. Clinical assessment is difficult and unreliable however Ultrasonography (USG) has been an accepted method for diagnosis of focal & diffuses hepatic lesions because of its rapidity in performance & high sensitivity. 1 It is cheaper, easily available, effective, quick, painless, can be repeated, non-invasive with no radiation hazard. USG gives valuable information regarding site, size, number and nature of lesions with their relation to surrounding structures. With development of high frequency transducer, it has found important applications for imaging liver, spleen, kidneys and other abdominal organs. 2 Focal hepatic lesions are frequently missed with one modality, and then detected with another. 3 USG is used as first line imaging investigation in patients with jaundice, right upper quadrant pain and hepatomegaly 4 . It's preferred to assess patients considered for resection of primary or metastatic liver tumors. Due to its ability to image in any oblique plane it can localize lesions to an anatomic segment or sub segment of the liver. In addition, it can be used as imaging guide for FNAC (Fine Needle Aspiration Cytology) or therapeutic drainage of abscesses.The guided FNAC of the liver is a safe, simple, cost-effective and accurate method for cytological diagnosis of hepatic lesions like diffuse, focal, nodular and cystic lesions with good sensitivity and specificity. 5 This study has been conducted on 118 patients to diagnose hepatic lesions by USG and to assess the validity in relation to FNAC diagnosis.

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“…Procedures such as sputum cytology or fine-needle puncture aspiration have proved their usefulness in the diagnosis of pulmonary lesions in which the diagnosis of pulmonary amoebiasis was not initially suspected [18,19]. Moreover, in cases of pulmonary amoebiasis without data indicating intestinal and/or hepatic repercussions, which have to be distinguished from other processes, such as bacterial abscesses, neoplasias, empyema and tuberculosis [20], the combination of trophozoite visualisation through cytological sputum examination with DNA extraction techniques has proved to be of Data are taken from [5].…”

Section: Genus Entamoebamentioning

confidence: 99%

Protozoa in respiratory pathology: a review

Martínez‐Girón¹,

Esteban²,

Ribas³

et al. 2008

Eur Respir J

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Among the micro-organisms that may affect the respiratory apparatus are the protozoa. The diseases they may give rise to constitute a relatively uncommon group of respiratory ailments with, in the majority of cases, an underlying clinical situation corresponding to states of suppressed immunity (AIDS, transplants, malign haemopathies, corticotherapy, etc.). Other factors, such as visits to endemic areas and immigration, also have to be taken into account.In view of the probable increase in the number of cases and the appearance of new emerging diseases, it is the intention of the present work to review the publications available, in different fields of medicine, that refer to the principal kinds of protozoa (Entamoeba,

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Amoebiasis: diagnosis by aspiration and exfoliative cytology

Cited by 20 publications

References 5 publications

Amebic Liver Abscess: Fine Needle Aspiration Diagnosis

Amebic Liver Abscess: Fine Needle Aspiration Diagnosis

Sonographic Evaluation of Focal and Diffuse Hepatic Lesions

Protozoa in respiratory pathology: a review

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