1984
DOI: 10.1007/bf00429720
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Amoxapine and amitriptyline

Abstract: Speed of onset of antidepressant effect was studied in 20 depressed outpatients assigned double-blind to equipotent doses of amoxapine or amitriptyline. In counter-balanced order, each patient had 2 periods of 3 weeks on active agent interspersed with 2 similar periods of placebo control. On daily and weekly self-ratings, amoxapine was found to reduce symptoms significantly more rapidly than amitriptyline. Psychiatrist-ratings were consonant with self-reports.

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Cited by 14 publications
(9 citation statements)
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“…McNair and Kahn (1984) found a slight but significant correlation between the CDS score and memory test performance (Sternberg Memory Scan, Digit Symbol Substitution Test) but not with the Posner letter identification task. A higher cognitive complaints score was associated with 'faster and more accurate performance', suggesting that non-cognitive factors influenced the self-reports.…”
Section: Discussionmentioning
confidence: 90%
See 1 more Smart Citation
“…McNair and Kahn (1984) found a slight but significant correlation between the CDS score and memory test performance (Sternberg Memory Scan, Digit Symbol Substitution Test) but not with the Posner letter identification task. A higher cognitive complaints score was associated with 'faster and more accurate performance', suggesting that non-cognitive factors influenced the self-reports.…”
Section: Discussionmentioning
confidence: 90%
“…The Cognitive Difficulties Scale (McNair and Kahn, 1984) is a short questionnaire which, its authors claim, reliably detects the effect of drugs for memory. We have assessed the validity of this scale (adapted in French) in a large sample comprising individuals aged between 45 and 75 years with no serious medical or psychiatric disorders.…”
Section: Derouesnb M J Dealberto P Boyer Et Almentioning
confidence: 99%
“…Subjective cognitive complaints were measured using the Cognitive Difficulties Scale (McNair & Kahn, 1984). This measure includes 26 items assessing a broad range of subjective complaints regarding basic neurocognitive functions and their effects on daily functioning (e.g., “I forget appointments, dates, or meetings”, “I fail to recognize people I know”).…”
Section: Study Two: Methodsmentioning
confidence: 99%
“…We evaluated global cognitive performance with the MMSE, presented above. In addition, the subjective Cognitive Difficulties Scale (CDS, McNair & Kahn, 1983) was used to assess memory complaints in daily life. This scale is a 39-item self-report measure of memory and general cognitive complaints using a Likert-type scale.…”
Section: Methodsmentioning
confidence: 99%