Amperometric biosensor based on diamond paste for the enantioanalysis of l-lysine

Electrochemical Methods for the Analysis of Clinically Relevant Biomolecules

“…Many sensors for amino acids can distinguish between the D and L enantiomers of amino acids. Enantiomeric discrimination can be achieved using (i) stereoselective enzymes such as Dmethionine oxidase, 233 D-leucine oxidase, 233 and L-lysine oxidase; 231 (ii) MIPs for selective detection of L-histidine 236,242 and L-tryptophan; 240 and (iii) stereoselective electrode coating materials such as β-cyclodextrin at an optimized temperature for selective detection of L-tryptophan 243 and dsDNA probes in the presence of Cu(II) for detection of L-tryptophan. 244 A variety of electrocatalytic electrode coating materials have been utilized to construct amino acid biosensors, including cobalt phthalocyanine, 245 poly epichrome black T, 246 cobalt-exchanged zeolite Y, 247 iron oxide/hexacyanoferrate core−shell, 248 and poly(o-aminophenol), 249 for cysteine analysis; a composite of nickel oxide nanoparticles, DNA, and osmium(III) complex for homocysteine analysis; 250 overoxidized polyimidazole, 251 salicylaldehyde modified chitosan, 252 acetaminophen, 253 poly glutamic acid, 254 and 3,4-dihydroxybenzaldehyde-2,4-dinitrophenylhydrazone, 255 for tryptophan analysis; and an electropolymerized film of 1,8,15,22-tetraaminophthalocyanato-Cu (II) for methionine analysis, 256 and ZnO/Zn 3 [Fe(CN) 6 ] 2− for tyrosine analysis.…”

“…An enzymatic amperometric sensor for l -lysine was designed on the basis of the impregnation of l -lysine oxidase in a diamond paste . This sensor exhibited a linear response toward l -lysine in the range from 1 to 100 nM, with a LOD of 4 pM.…”

“…Many sensors for amino acids can distinguish between the d and l enantiomers of amino acids. Enantiomeric discrimination can be achieved using (i) stereoselective enzymes such as d -methionine oxidase, d -leucine oxidase, and l -lysine oxidase; (ii) MIPs for selective detection of l -histidine , and l -tryptophan; and (iii) stereoselective electrode coating materials such as β-cyclodextrin at an optimized temperature for selective detection of l -tryptophan and dsDNA probes in the presence of Cu­(II) for detection of l -tryptophan …”

Synthesis, binding ability, and cell cytotoxicity of fluorescent probes for l‐arginine detection based on naphthalene derivatives: Experiment and theory

“…Detection methods for Arg have been reported based on traditional determination, such as high‐performance liquid chromatography, gas phase chromatography, ion exchange chromatography, and electrochemical method. The above methods have some deficiency, such as expensive instruments, poor repetitiveness, and selectivity . The disadvantages of most used approaches are being time‐consuming and expensive and requiring skillful labor techniques .…”

Electrochemical Imprinted Polycrystalline Nickel–Nickel Oxide Half-Nanotube-Modified Boron-Doped Diamond Electrode for the Detection of l-Serine

“…BDD electrodes outperform conventional electrodes in terms of stability, chemical inertness, potential window width, and low background current . Combining these superior properties of BDD electrodes with the merits of electrochemical biosensors, such as sensitivity and fast response, amperometric biosensors based on BDD electrodes have attracted the interest of many researchers. − The use of nickel microparticle modified BDD electrodes was reported by Toghill et al, with detection limits well in the range of blood glucose levels (and lower) reported. In Hutton et al’s work, the effect of the size of nickel hydroxide nanoparticles (NPs) on electrocatalytic activity was investigated .…”