Amperometric Biosensor Based on Glucose Dehydrogenase and Plasma-polymerized Thin Films

Hiratsuka, Atsunori; Fujisawa, Kohta; Muguruma, Hitoshi

doi:10.2116/analsci.24.483

Cited by 24 publications

(7 citation statements)

References 27 publications

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“…There are three main parts of a biosensor: (i) the biological recognition elements that differentiate the target molecules in the presence of various chemicals, (ii) a transducer that converts the biorecognition event into a measurable signal, and (iii) a signal processing system that converts the signal into a readable form [19–21]. The molecular recognition elements include receptors, enzymes, antibodies, nucleic acids, microorganisms and lectins [22,23].…”

Section: Basic Principles Of Glucose Biosensorsmentioning

confidence: 99%

Glucose Biosensors: An Overview of Use in Clinical Practice

Yoo

Lee

2010

Sensors

949

556

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Blood glucose monitoring has been established as a valuable tool in the management of diabetes. Since maintaining normal blood glucose levels is recommended, a series of suitable glucose biosensors have been developed. During the last 50 years, glucose biosensor technology including point-of-care devices, continuous glucose monitoring systems and noninvasive glucose monitoring systems has been significantly improved. However, there continues to be several challenges related to the achievement of accurate and reliable glucose monitoring. Further technical improvements in glucose biosensors, standardization of the analytical goals for their performance, and continuously assessing and training lay users are required. This article reviews the brief history, basic principles, analytical performance, and the present status of glucose biosensors in the clinical practice.

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Section: Basic Principles Of Glucose Biosensorsmentioning

confidence: 99%

Glucose Biosensors: An Overview of Use in Clinical Practice

Yoo

Lee

2010

Sensors

949

556

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“…The immobilization of proteins by embedding in PPF plays a role in passivation against leaching and anti‐fouling, while retaining the activity of the proteins (Figure 1c). 59 In the case of proteins half‐buried in PPF (Figure 1c and 2c), the active site can be used for further processing e.g., biospecific interaction using PPF functionality vice versa,39–41, 55 because some proteins (glucose oxidase,57–59 glucose dehydrogenase,60 streptavidin,39–41, 55 and antibodies42) retain their activity even after direct exposure in plasma.…”

Section: Fundamental Aspects Of Plasma‐polymerized Films For Biochip mentioning

confidence: 99%

Plasma‐Polymerized Films for Biochip Design

Muguruma¹

2010

Plasma Processes & Polymers

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Developments in plasma‐polymerized films used for the design of chip‐based biosensors, commonly referred to as biochips, are described. Plasma‐polymerized films are suitable for the design of an interface between biological components and physical transducers, which are the two well‐known main parts of biochips. The roles and advantages of plasma‐polymerized films in biochip design are highlighted. Mainly, plasma‐polymerized films can play an important role in the control and manipulation of biological components on different spatial regions (patterning), while retaining their activity. In addition, dry‐process‐based plasma‐polymerization are compatible with biochip fabrication processes.

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“…Various factors influence the reaction of an electrochemical biosensor and in this manner the biosensor gives us the accurate results. There are three primary fragments of a biosensor : (I) the organic acceptance component that separate the objective atoms within the sight of different synthetic compounds, (ii) a transducer which changes over the bio recall occasion into a quantifiable sign, and (iii) the sign of framework which changes a sign into a legible structure [6][7][8]. Here we mainly discuss about previous three generations of biosensors and how the present technique is useful than the previous techniques.…”

Section: Introductionmentioning

confidence: 99%

Detection of Diabetes using Biosensors

Venkateswarulu*,

Hitesh

et al. 2019

IJRTE

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Diabetes is the widespread disease in the world. During the last few decades there is a huge increase in the number of diabetic patients. Biosensor is a device which is used to detect diabetes. It converts biological reading into electrical pursuing that helps the patients to predict their diabetic levels. It consists of a biological recognition element and a chemical sensor. They are high-technology tracking tools that measures sugar levels in a quick, highly sensible fashion. We mainly focus on the glucose-oxidase biosensor which uses machine learning techniques and regression methods. Detection of diabetes can be done in many forms like with a radiofrequency biosensor chip, optical fiber biosensor, micro-fluidic biosensor. Optical biosensor is placed in contact lens to detect glucose levels within the tears and give the accurate prediction. There were some early versions of glucose-sensing devices. There are different existing techniques for the detection. But the preferred method is using the continuous glucose observing system. This method offers a good control of diabetes by using real time data. However, there are few provokes identified with the accomplishment of precise and dependable glucose observing. Further consistency and improvements in the development of biosensors to meet their goals are required.

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Amperometric Biosensor Based on Glucose Dehydrogenase and Plasma-polymerized Thin Films

Cited by 24 publications

References 27 publications

Glucose Biosensors: An Overview of Use in Clinical Practice

Glucose Biosensors: An Overview of Use in Clinical Practice

Plasma‐Polymerized Films for Biochip Design

Detection of Diabetes using Biosensors

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