Amphiphilic diblock copolymers based on sucrose methacrylate: RAFT polymerization and self-assembly

Triblock Copolymers Based on Sucrose Methacrylate and Methyl Methacrylate: RAFT Polymerization and Self‐Assembly

“…Moreover, they acted as emulsifier for water/oil emulsion. Diblock copolymers based on SMA and methyl methacrylate synthesized by RAFT [ 17 ] presented similar properties compared with those copolymers from ref. [18].…”

“…In the last decade, our group has reported the synthesis of carbohydrate‐based monomers, [ 14,15 ] and their homo and copolymers via conventional [ 14–16 ] and controlled radical polymerization. [ 17,18 ] Amphiphilic diblock copolymers based on sucrose methacrylate (SMA) and alkyl methacrylates [ 18 ] synthesized by atom transfer radical polymerization (ATRP) presented the capability of self‐assembly in solution and in solid‐state‐forming lamellar structures. Moreover, they acted as emulsifier for water/oil emulsion.…”

“…This characteristic is important because SMA polymerization is slower compared with others methacrylates and PSMA molar fraction in the copolymers may be low. [ 17,18 ] Besides amphiphilicity, SMA‐mers in polymer chain may endow biodegradability, biocompatibility and also specific biological interactions, as reported for others carbohydrates. [ 19–22 ] Because of this, polymers based on carbohydrate (meth)acrylates are of crescent interest for biological and biomedical applications, such as drug delivery systems, synthetic skin, cellular culture matrices, and others applications, such as, surfactants, membranes, etc.…”

Macroporous hydrogels based on carbohydrates monomethacrylates and dimethacrylates: singular properties from carbohydrate‐based crosslinkers

“…Since the synthesis of carbohydrate‐based polymers and hydrogels by the chemo‐enzymatic route reported by Dordick and coworkers, many monomers, crosslinkers and polymeric materials based on carbohydrates (named glycopolymers) have been prepared . In this context, our research group has been investing great efforts in developing new polymeric materials based on carbohydrates, such as polymers, copolymers and hydrogels based on fructose, glucose and sucrose methacrylates …”

“…[6][7][8][9] In this context, our research group has been investing great efforts in developing new polymeric materials based on carbohydrates, such as polymers, copolymers and hydrogels based on fructose, glucose and sucrose methacrylates. [10][11][12][13][14] The carbohydrate moieties in glycopolymers are capable of playing some specific biological interactions, such as interactions between glucose moieties with the lectin Concanavalin A [15][16][17] and interactions between fructose moieties with the glucose receptor GLUT5 (receptor overexpressed in the cell membrane of mammalian cancer cells). [18][19][20] Moreover, hydrophilic polymers such as polysaccharides and glycopolymers present anti-fouling properties that diminish protein and bacterial adhesion, avoiding platelet adhesion, inflammation, device failure, blood clots, and so on.…”