Amphiphilic rhomboidal metallacycles with aggregation-induced emission and aggregation-caused quenching luminogens for white-light emission and bioimaging

Abstract

Three rhomboidal metallacycles are formed by metal-ligand interactions. Due to the integration of AIEgens and ACQphores, metallacycles exhibit tunable emission. And the amphiphilic structures promote the formation of micelles used for cell imaging.

Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy

“… ( A–C ) Partial 31 P NMR (CDCl 3 /CD 2 Cl 2 ; 297 K) spectra and ( D–H ) 1 H NMR spectra (DMSO- d 6 ; 297 K) of ( A and D ) the free 60° diplatinum(II) acceptor ( 5 ), ( F ) phenoxy-boron dipyrromethene (BODIPY) ( 3 ), ( H ) phenylthiol-BODIPY ( 4 ), ( B and E ) metallacycle 1 , and ( C and G ) metallacycle 2 . Experimental (red) and calculated (blue) ESI-TOF-MS spectra of ( I ) [ 1 – 5OTf] 5+ and ( J ) [ 2 – 5OTf] 4+ .…”

“…The high morbidity and mortality of cancer have motivated the search for effective tumor therapy, which remains as a challenge in medicine. Currently, tumors are treated mainly by surgery, chemotherapy, and radiotherapy ( 1 – 4 ). Among the recent developments in diagnostic equipment and treatment technology, photodynamic therapy (PDT), which involves the use of photosensitizers and specific light activation, has emerged as an effective treatment modality ( 5 – 11 ).…”

Aggregate emission behaviors and reversible mechanofluorochromic properties of α-cyanostilbene functionalized indolo[3,2-b]carbazole derivatives

“…However, a large number of traditional organic fluorescent materials show aggregation-caused quenching (ACQ), which originates from π–π stacking or other non-radiative pathways. 2 The discovery and development of aggregation-induced emission (AIE) and aggregation-induced emission enhancement (AIEE) materials completely alleviated the ACQ problem. 3 As is known, most of MFC materials rely on intermolecular stacking patterns.…”

Supramolecular coordination complexes (SCCs) with aggregation-induced emission forin vitrophotodynamic therapy

“…6 With the development of supramolecular chemistry, supramolecular coordination complexes (SCCs) have received considerable critical attention. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] SCCs, including two-dimensional metallacycles and three-dimensional metallacages, are established by coordination-driven self-assembly between organic donors and metal acceptors according to strictstoichiometric ratios. [22][23][24][25] Due to the interaction between the building components, SCCs exhibit superior performance over independent building components and using SCCs becomes an effective strategy for constructing functional materials.…”